ArticleCureus2025
Changes in Kidney Function Following Living Donor Nephrectomy: A Retrospective, Single-Center, Descriptive Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background Kidney transplantation is the best possible option for patients reaching end-stage renal disease. Despite the excellent outcomes for recipients in terms of graft survival, the evidence regarding outcomes for donors is conflicting, and there is uncertainty regarding the long-term complications of kidney donation. Thus, our study aimed to assess the change in kidney function following donor nephrectomy and identify the associated comorbidities in a Sri Lankan cohort. Methodology This descriptive retrospective study was conducted at the donor clinic of Unit 1 at the National Hospital of Sri Lanka from July 2021 to November 2021. A total of 102 donors who had undergone donor nephrectomy since 2005 were included. Results The mean duration of the study population since donation was six years, with a standard deviation of ±3.20. The minimum duration since donation was one year, and the maximum was 14 years. The median interquartile range (IQR) preoperative glomerular filtration rate (GFR) was 94.50 (19) ml/min; the GFR on discharge was 66.50 (29) ml/min; and the current median GFR was 73.86 (23.31) ml/min. These changes in the GFR were statistically insignificant, with a p-value of 0.062. The preoperative estimated glomerular filtration rates (eGFRs) of all 102 donors (100%) exceeded 60 ml/min/1.73 m
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