ArticleCureus2025
Bilateral Cystoid Macular Edema After Light Treatment With Light-Adjustable Lens.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Light-adjustable lenses (LALs) allow for visual acuity (VA) adjustment after cataract surgery, using ultraviolet (UV) light therapy. UV-induced cystoid macular edema (CME) is not well documented. We report the first case of bilateral CME after UV light therapy with LAL. An 81-year-old woman underwent uncomplicated staged bilateral cataract extraction with LAL implantation. Two days after the second UV light adjustment, she had bilateral decreased VA and a new-onset bilateral CME. UV treatments were halted, and she was started on topical nonsteroidal anti-inflammatory drug (NSAID) therapy and prednisolone. CME completely resolved within three weeks following onset. Topical NSAID and prednisone drops were continued until the completion of all light treatments, followed by a slow taper over one month. We hypothesize that UV light can contribute to CME via multiple mechanisms, including UV-activated macromer byproducts, direct UV-induced injury, or ultraviolet B (UVB) disrupting the blood-aqueous barrier. Clinicians should be aware of this complication and maintain a low threshold for deferring light therapy and initiating topical treatment.
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