Evidence map›Paper›PMID 40978824›Full record

ArticleCureus2025

Pregnancy-Induced Thrombotic Thrombocytopenic Purpura Complicated by Atypical Posterior Reversible Encephalopathy Syndrome and Acute Pancreatitis: A Rare Presentation.

Madhu Kiran Reddy Turupu, Nikhil Kumar Balagoni, Rithik Naik Korra, Uma Shailendri Rayudu, Neha Bijjigum, Jaswanth Soorisetty, Vishal Loney, Praveen Bharath Saravanan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Madhu Kiran Reddy TurupuGeneral Medicine, Osmania Medical College, Hyderabad, IND.
Nikhil Kumar BalagoniInternal Medicine, Osmania Medical College, Hyderabad, IND.
Rithik Naik KorraInternal Medicine, Osmania Medical College, Hyderabad, IND.
Uma Shailendri RayuduInternal Medicine, Gitam Institute of Medical Sciences and Research, Visakhapatnam, IND.
Neha BijjigumInternal Medicine, Kakatiya Medical College, Warangal, IND.
Jaswanth SoorisettyInternal Medicine, Saint James School of Medicine, Arnos Vale, VCT.
Vishal LoneyInternal Medicine, Osmania Medical College, Hyderabad, IND.
Praveen Bharath SaravananInternal Medicine, K.A.P. Viswanatham Government Medical College, Tiruchirappalli, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy is a documented trigger for thrombotic thrombocytopenic purpura (TTP), a rapidly progressing condition that is often misdiagnosed as HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome. Here, we present the case of a 28-year-old pregnant female, gravida 2 para 1, who was admitted for complaints of seizures, vomiting, fever, decreased perception of fetal movements, and visual impairment. She was found to have posterior reversible encephalopathy syndrome, acute kidney injury, and acute pancreatitis, along with her diagnosis of TTP. She improved with plasma exchange and recovered well. Maternal and fetal survival in TTP patients depends heavily on early diagnosis, swift initiation of therapeutic plasma exchange, and vigilant monitoring throughout pregnancy and the postpartum period. This case emphasizes the importance of ruling out differentials often grouped with TTP in resource-limited settings.

Indexed as

acute kidney injuryacute pancreatitisplasma exchangeposterior reversible encephalopathy syndromepregnancythrombotic thrombocytopenic purpura

Identifiers

PMID40978824
PMCPMC12445238

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.