Evidence map›Paper›PMID 40978737›Full record

ArticleFrontiers in medicine2025

Late vs. early intrauterine blood transfusion in fetal anemia: impact on maternal and neonatal outcomes.

Adva Cahen Peretz, Lilah Tsaitlin-Mor, Gideon Leibner, Sarah M Cohen, Danielle Amosi-Victor, Nitsan Haham, Tomer Shwartz, Nili Yanai, Shay Porat, Simcha Yagel and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Adva Cahen PeretzHadassah Medical Center, Jerusalem, Israel.
Lilah Tsaitlin-MorHadassah Medical Center, Jerusalem, Israel.
Gideon LeibnerHadassah Medical Center, Jerusalem, Israel.
Sarah M CohenHadassah Medical Center, Jerusalem, Israel.
Danielle Amosi-VictorHadassah Medical Center, Jerusalem, Israel.
Nitsan HahamFaculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Tomer ShwartzHadassah Medical Center, Jerusalem, Israel.
Nili YanaiHadassah Medical Center, Jerusalem, Israel.
Shay PoratHadassah Medical Center, Jerusalem, Israel.
Simcha YagelHadassah Medical Center, Jerusalem, Israel.
Dan V ValskyHadassah Medical Center, Jerusalem, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Optimal timing of final intrauterine transfusion (IUT) and delivery in fetal anemia remains controversial, balancing procedural risks against prematurity complications. Our objective is to evaluate the safety and effectiveness of extending IUT beyond 34 weeks gestation in appropriately selected cases. Methods: Retrospective cohort study comparing pregnancies receiving late IUT (≥34 weeks, Results: Late IUT showed no increase in procedure-related complications (0% vs. 20.0%, Discussion: Extending IUT beyond 34 weeks in selected cases is safe and associated with improved obstetric and neonatal outcomes, supporting reconsideration of traditional gestational age limits for IUT.

Indexed as

alloimmunizationfetal anemiahemolytic disease of the fetus and newborn (HDFN)intrauterine blood transfusion (IUT)late gestation IUTneonatal morbidityprematurity complications

Identifiers

PMID40978737
PMCPMC12446343

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.