ArticleFrontiers in medicine2025
Microbial profile and antimicrobial resistance patterns of ocular infection pre/during and post the COVID-19 pandemic.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: This research investigated the distribution characteristics and antimicrobial resistance patterns of pathogenic microorganisms in patients with ocular infection before/during and post the coronavirus disease 2019 (COVID-19) pandemic. Methods: This retrospective study, conducted at the Second People's Hospital of Jinan, Shandong, China, analyzed the microorganism cultures of specimens (eye secretions, anterior chamber fluid, and vitreous body) obtained from patients with ocular infection (including ocular trauma, endophthalmitis, keratitis, conjunctivitis, dacryocystitis, and blepharitis) pre/during (from May 2019 to January 2023, A group) and after (from February 2023 to November 2024, B group) the COVID-19 pandemic. The microorganism species was analyzed using a microbial identification instrument, and antimicrobial susceptibility testing was carried out using Kirby-Bauer (K-B) disk diffusion method. Results: 465 and 319 strains of pathogenic microorganisms were obtained from specimens in A and B groups, respectively. The isolates of Conclusion: Changes in resistance patterns were observed after the COVID-19 pandemic, which might be influenced by relaxation of infection prevention and control (IPC) measures. These alterations might be also attributed to other factors, such us changes over time or the use of antibiotics. And further investigation was required to establish causality.
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