Evidence map›Paper›PMID 40978723›Full record

ArticleFrontiers in medicine2025

Case Report: The first account of primary myeloid sarcoma of the testis combined with ipsilateral epididymal epithelioid hemangioendothelioma.

Xi Chen, Li Liu

Abstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xi ChenDepartment of Pathology, Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Li LiuDepartment of Pathology, Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report describes a 35-year-old male with primary myeloid sarcoma (MS) of the testis and concurrent ipsilateral epididymal epithelioid hemangioendothelioma (EHE)-an exceptionally rare combination. Myeloid sarcoma typically involves the skin and bone, but testicular involvement is rare, particularly as an isolated tumor without hematologic malignancy. This makes diagnosis challenging. Epithelioid hemangioendothelioma is a rare vascular tumor, typically found in the liver, lungs, and bones, and epididymal EHE is scarcely reported. The patient had a left testicular nodule for 6 months and experienced pain for 2 days. Ultrasound and MRI revealed abnormalities in the left testis and epididymis. Histopathological examination of the epididymal biopsy showed tumor cells with specific morphological features, and immunohistochemistry (IHC) indicated CD31(+), CD34(+), Fli-1(+), ERG(+), Ki-67(+5%+), along with WWTR1-CAMTA1 gene fusion by fluorescence

Indexed as

epididymis tumorsepithelioid hemangioendotheliomaimmunohistochemistrymyeloid sarcomatestis tumorsWWTR1-CAMTA1 gene

Identifiers

PMID40978723
PMCPMC12446354

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.