ArticleCase reports in women's health2025
Acute non-puerperal uterine inversion caused by a giant uterine leiomyoma with angioleiomyomatous features: A case report.
Article in Case reports in women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Non-puerperal uterine inversion is an extremely rare condition most often associated with uterine tumors. A 48-year-old woman presented with sudden vaginal bleeding and a large protruding mass. Emergency surgery revealed complete uterine inversion caused by a giant pedunculated mass arising from the uterine fundus. The tumor was excised vaginally, and the uterus was manually repositioned. Because multiple fibroids were also present and fertility was not desired, a total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed. Histopathological examination revealed a leiomyoma with prominent angioleiomyomatous features, characterized by spindle cells surrounding thick-walled vascular structures and immunopositivity for desmin, smooth muscle actin, and progesterone receptor. The postoperative course was uneventful, and no recurrence was observed during 60 months of follow-up. This case highlights a rare morphological variant of uterine leiomyoma presenting with acute non-puerperal inversion and emphasizes the importance of early recognition and prompt surgical management.
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