ArticleBioinformation2025
Enrichment-induced behavioural changes in MPTP mice.
Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 authors.
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Abstract
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor and non-motor deficits due to dopaminergic neuron loss. Neuro-protective effects of enriched environment have been well established. Therefore, it is of interest to examine the effects of enriched housing in a 1-methyl-4- phenyl 1, 2, 3, 6-tetrahydropyridine (MPTP)-induced mouse model of PD. Thirty-two male C57BL/6 mice were divided into standard and enriched housing groups, with MPTP or saline treatment. MPTP mice in standard housing showed impaired motor function, whereas MPTP mice in enriched housing did not show decline in motor function, demonstrating the beneficial effects of environmental enrichment in MPTP mice.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.