Evidence map›Paper›PMID 40978639›Full record

ArticleBioinformation2025

Effect of root conditioning agents on teeth periodontal using Scanning electron microscopy.

Balaji V R, Manikandan D, Varshiny M D

Abstract read
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Balaji V RDepartment of Periodontics & Implant Dentistry, CSI College of Dental Sciences and Research, Madurai, Recognised by Government of India and Dental Council Of India, New Delhi, Affliated to The Tamil Nadu Dr MGR Medical University, Chennai, India.
Manikandan DDepartment of Periodontics & Implant Dentistry, CSI College of Dental Sciences and Research, Madurai, Recognised by Government of India and Dental Council Of India, New Delhi, Affliated to The Tamil Nadu Dr MGR Medical University, Chennai, India.
Varshiny M DDepartment of Periodontics & Implant Dentistry, CSI College of Dental Sciences and Research, Madurai, Recognised by Government of India and Dental Council Of India, New Delhi, Affliated to The Tamil Nadu Dr MGR Medical University, Chennai, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanical instrumentation of root surfaces results in the formation of a smear layer that may impede the reattachment of connective tissue. Root conditioning agents are employed to remove the smear layer, expose collagen fibres and facilitate improved tissue regeneration. Therefore, it is of interest to assess the efficacy of five root conditioning agents-20% citric acid, 17% EDTA, 37% phosphoric acid, 250 mg/mL tetracycline hydrochloride and 0.8% hyaluronic acid-using scanning electron microscopy. Tetracycline hydrochloride showed the greatest efficacy, exhibiting a significantly higher number of patent dentinal tubules compared to other agents. Thus, root surface conditioning enhances biocompatibility, promotes fibroblast adhesion and contributes to favourable periodontal healing and successful surgical outcomes.

Indexed as

citric acidEDTAHyaluronic acidperiodontal diseasePhosphoric acidRoot ConditioningScanning Electron Microscopy (SEM)Tetracycline HCL

Identifiers

PMID40978639
PMCPMC12449567

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.