ArticleBioinformation2025
Role of salivary MMP-9 in OSCC detection and diagnosis: A comprehensive clinical assessment.
Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Diagnostic utility of salivary LDH and MMP-9 in differentiating oral cancer from potentially malignant disorders.Bioinformation · 2026Article
- The Role of Inflammasomes in Chronic Oral Inflammatory Disease and Oral Cancer: A Narrative Review.Dentistry journal · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An Enzyme-Linked Immunosorbent Assay (ELISA) to measure the salivary Matrix metalloproteinase-9 (MMP-9) levels among squamous cell carcinoma patients was used. Thirty of the sixty participants in the research had a verified diagnosis of oral SCC, whereas the remaining twenty were healthy controls. Salivary MMP-9 levels were extracted by centrifugation and measured using ELISA. The results were compared between oral SCC patients and controls. Participants with oral squamous cell carcinoma had considerably greater mean salivary MMP-9 levels than healthy subjects (p<0.05). Thus, individuals with oral squamous cell carcinoma have average salivary MMP-9 levels, and those with poorly differentiated oral squamous cell carcinoma have even higher levels.
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Registered trials
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