Evidence map›Paper›PMID 40978566›Full record

ArticleMaterials today. Chemistry2024

Electrostatic Loading and Photoredox-Accelerated Release of Antibiotics from Oligoviologen-Crosslinked Hydrogels Using Red Light.

J M Dorsainvil, M S Palmquist, J Yang, A O Delawder, M K Danielson, Y Zhang, T M Saak, M C Gruschka, X Kong, T A Wencewicz and 1 more

Abstract read
In one paragraph

Article in Materials today. Chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Enhanced Electrochromic Smart Windows Based on Supramolecular Viologen Tweezers.Chemistry of materials : a publication of the American Chemical Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

J M DorsainvilDepartment of Chemistry, Washington University, St. Louis, MO 63130, United States.
M S PalmquistDepartment of Chemistry, Washington University, St. Louis, MO 63130, United States.
J YangDepartment of Chemistry, Washington University, St. Louis, MO 63130, United States.
A O DelawderDepartment of Chemistry, Washington University, St. Louis, MO 63130, United States.
M K DanielsonDepartment of Chemistry, Washington University, St. Louis, MO 63130, United States.
Y ZhangDepartment of Chemistry, Washington University, St. Louis, MO 63130, United States.
T M SaakDepartment of Chemistry, Washington University, St. Louis, MO 63130, United States.
M C GruschkaDepartment of Chemistry, Washington University, St. Louis, MO 63130, United States.
X KongDepartment of Chemistry, Washington University, St. Louis, MO 63130, United States.
T A WencewiczDepartment of Chemistry, Washington University, St. Louis, MO 63130, United States.
J C BarnesDepartment of Chemistry, Washington University, St. Louis, MO 63130, United States.

Funding

STRUCTURAL, MECHANISTIC, & EVOLUTIONARY CHARACTERIZATION OF TETRACYCLINE DESTRUCTASESU01AI123394 · NIAID · WASHINGTON UNIVERSITY · PI DANTAS, GAUTAM, WENCEWICZ, TIMOTHY ADAM · 2020 to 2025
$4.1M
NIAID NIH HHS U01 AI123394
6 · The paper itself

Abstract

Hydrogel drug delivery is the subject of an ever-expanding industry where delivery occurs by numerous methods, many of them passive in nature. On-command, stimuli-driven release, particularly using light to initiate spatiotemporal, controlled release of cargo is a more attractive approach than passive release methods. Here, we report a novel method for electrostatically loading negatively charged dye and antibiotic cargo in biocompatible, oligoviologen-crosslinked hydrogels equipped with an integrated Aza-boron-dipyrromethene (Aza-BODIPY) photocatalyst. Following loading, the release of the electrostatically bound cargos can be accelerated upon irradiation with red light (660 nm) through a photoinduced electron transfer (PET) process that reduced the oligoviologen subunits. A free radical polymerization method was used to fabricate the hydrogels with a hydroxyethyl acrylate backbone, co-crosslinked by a viologen hexamer (

Indexed as

AntibioticDrug DeliveryHydrogelPhotoredoxRed LightViologen

Identifiers

PMID40978566
PMCPMC12445729

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.