Evidence map›Paper›PMID 40978548›Full record

ArticleJournal of pain research2025

Erector Spinae Plane versus Pectoralis Nerve Block for Mastectomy in Cancer Patients: A Retrospective, Multicenter Cohort Study.

Edward N Yap, Julia Wei, Curtis Darling, Elizabeth Linehan, Matthias Behrends, Kevin P Ng

Abstract read
In one paragraph

Article in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Edward N YapDepartment of Anesthesia, The Permanente Medical Group, Kaiser Permanente South San Francisco, South San Francisco, CA, USA.ORCID 0000-0001-7992-5572
Julia WeiDivision of Research, Kaiser Permanente Northern California, Oakland, CA, USA.
Curtis DarlingDepartment of Anesthesia, The Permanente Medical Group, Kaiser Permanente Santa Clara, Santa Clara, CA, USA.
Elizabeth LinehanDepartment of General Surgery, Division of Breast Surgical Oncology, the Permanente Medical Group, Kaiser Permanente San Francisco, San Francisco, CA, USA.
Matthias BehrendsDepartment of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, CA, USA.
Kevin P NgDepartment of Anesthesia, The Permanente Medical Group, Kaiser Permanente Walnut Creek, Walnut Creek, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mastectomy patients require effective acute postoperative pain management. Regional anesthesia techniques such as fascial plane blocks are important pain treatment modalities to address pain control. This study compared the effects of the erector spinae plane (ESP) block versus the pectoralis nerve (PECS) block in providing postoperative analgesia for mastectomy patients. Methods: This retrospective study included 517 breast cancer patients undergoing mastectomy from 2017 to 2020, with 428 receiving a PECS block and 89 an ESP block. The primary outcome examined was total opioid use during hospital stay measured in morphine milligram equivalents (MME). Secondary outcomes included length of hospital stay, post-anesthesia care unit (PACU) pain scores, PACU postoperative nausea and vomiting (PONV), 30-day readmission rates, and development of postmastectomy pain within six months of surgery. Results: No significant difference in median total opioid use between the ESP (53 MME (IQR: 38-80 MME)) and PECS (60 MME (IQR: 30-82.5 MME)) groups. Multivariable analysis confirmed no difference in total opioid consumption. There was no significant difference between the two groups in PACU average and maximum pain scores, PACU PONV, hospital length of stay, 30-day hospital readmission, and development of postmastectomy pain within six months of surgery. Conclusion: Compared to the PECS block, the ESP block demonstrated no significant difference in acute pain outcomes and recovery in patients undergoing mastectomy for breast cancer, with similar hospital discharge times and long-term outcomes.

Indexed as

breast cancererector spinae plane blockmastectomyopioid consumptionpectoralis nerve blockpostoperative analgesiaregional anesthesia

Identifiers

PMID40978548
PMCPMC12449883

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.