Evidence map›Paper›PMID 40978449›Full record

ArticleACS omega2025

Hemoglobin Oxygen Affinity Does Not Change in the Canine Model of Moderate Acute Normovolemic Hemodilution.

Ming Sheng, Weidan Li, Guoxing You, Ying Wang, Penglong Li, Shiyu Tao, Daoyuan Gao, Hong Zhou, Lian Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ming ShengAcademy of Military Science of the Chinese People's Liberation Army, Academy of Military Medical Sciences, No. 27 Taiping Road, Haidian, Beijing 100850, P. R. China.ORCID https://orcid.org/0000-0002-6824-5923
Weidan LiAcademy of Military Science of the Chinese People's Liberation Army, Academy of Military Medical Sciences, No. 27 Taiping Road, Haidian, Beijing 100850, P. R. China.
Guoxing YouAcademy of Military Science of the Chinese People's Liberation Army, Academy of Military Medical Sciences, No. 27 Taiping Road, Haidian, Beijing 100850, P. R. China.
Ying WangAcademy of Military Science of the Chinese People's Liberation Army, Academy of Military Medical Sciences, No. 27 Taiping Road, Haidian, Beijing 100850, P. R. China.
Penglong LiAcademy of Military Science of the Chinese People's Liberation Army, Academy of Military Medical Sciences, No. 27 Taiping Road, Haidian, Beijing 100850, P. R. China.
Shiyu TaoAcademy of Military Science of the Chinese People's Liberation Army, Academy of Military Medical Sciences, No. 27 Taiping Road, Haidian, Beijing 100850, P. R. China.
Daoyuan GaoAcademy of Military Science of the Chinese People's Liberation Army, Academy of Military Medical Sciences, No. 27 Taiping Road, Haidian, Beijing 100850, P. R. China.
Hong ZhouAcademy of Military Science of the Chinese People's Liberation Army, Academy of Military Medical Sciences, No. 27 Taiping Road, Haidian, Beijing 100850, P. R. China.ORCID https://orcid.org/0000-0003-2987-7781
Lian ZhaoAcademy of Military Science of the Chinese People's Liberation Army, Academy of Military Medical Sciences, No. 27 Taiping Road, Haidian, Beijing 100850, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAs the amount of hemoglobin (Hb) decreases during moderate acute normovolemic hemodilution (ANH), it is unclear whether the Hb-oxygen affinity (HOA) changes accordingly. Thus, this study aimed to explore changes in HOA during moderate ANH.

methodsA moderate ANH model of canine was established. Hemodynamic, blood gas, biochemical, oxygenation, and HOA-related parameters were measured.

resultsWith decreased Hb and hematocrit (HCT) levels during ANH, the temperature (T) and base excess (BE) decreased, while Cl

Identifiers

PMID40978449
PMCPMC12444557

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.