ReviewACS omega2025
Advanced NMR Screening: Unveiling Bioactive Compounds in Complex Molecular Mixtures.
Review in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- NMR Studies on Protein-Ligand Interactions.International journal of molecular sciences · 2026Review
- Cinnamon Bud Extract Is a Source of Biomolecules Active against the Aggregation and Condensation of Alzheimer's-Associated Tau Protein.Journal of agricultural and food chemistry · 2026Article
- Carrier-free self-assembled nanomedicines from natural small molecules: advances and perspectives for disease treatment.RSC advances · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nuclear magnetic resonance (NMR) spectroscopy represents an indispensable analytical tool for the structural and functional characterization of complex molecular mixtures, with significant applications in metabolomics, natural product discovery, and pharmaceutical analysis. A primary advantage of NMR is its capacity for the direct analysis of complex matrices, such as synthetic libraries and crude natural extracts, obviating the need for extensive chromatographic fractionation and thereby enabling the direct identification of bioactive constituents. This perspective provides a comprehensive review of ligand-observed NMR methodologies based on the principle that molecular binding is a prerequisite for biological function. Key techniques are systematically described, including Saturation Transfer Difference (STD), Transferred-NOE SpectroscopY (trNOESY), and methods based on relaxation rates (e.g.,
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.