Evidence map›Paper›PMID 40978299›Full record

ArticleAmerican journal of preventive cardiology2025

Contribution of high BMI to the global burden of cardiovascular disease among young adults aged 20-39 from 1990 to 2021: A systematic analysis for the Global burden of disease study 2021.

Jiaqi Hao, Mengkai Lu, Rui Sun, Xiuya Guan, Yuanlong Hu, Muxin Zhang, Zhiyuan Zhang, Xinhai Cui, Xin Wen, Chao Li and 1 more

Abstract read
In one paragraph

Article in American journal of preventive cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jiaqi HaoInnovation Research Institute of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Mengkai LuInnovation Research Institute of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Rui SunFirst Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Xiuya GuanInnovation Research Institute of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Yuanlong HuFirst Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Muxin ZhangFirst Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Zhiyuan ZhangInnovation Research Institute of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Xinhai CuiCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Xin WenCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Chao LiCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Chunxiao ZhangShaoxing Hospital of Traditional Chinese Medicine, Shaoxing 312000, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Understanding temporal trends in the burden of cardiovascular disease (CVD) attributable to high body mass index (BMI) in young adults is important for effective and targeted prevention strategies and measures. We aimed to provide comprehensive estimates of CVD deaths and disability-adjusted life-years (DALYs) rate attributable to high BMI in young adults aged 20-39 years at the global, regional, and national levels, as well as temporal trends from 1990 to 2021. Methods: We calculated age-standardized deaths rate and DALYs rate as well as estimated annual percentage changes (EAPC) using Global Burden of Disease (GBD) 2021 study data on deaths and DALYs for CVD attributable to high BMI among young adults aged 20-39 years. Results: Among non-communicable diseases, the burden of cardiovascular disease attributed to high BMI among young adults aged 20-39 years is much higher than chronic respiratory diseases, diabetes and kidney diseases, digestive diseases, and neoplasms. Among specific types of cardiovascular disease, ischemic heart disease accounted for the highest proportion, while stroke had the largest increase in the rate of DALYs. an increase in age-standardized DALYs rate over time in low-to-middle SDI regions, a decrease in age-standardized DALYs rate over time in high SDI regions, and a decrease in health inequality in 2021 compared with 1990. Conclusion: In 2021, the high burden of cardiovascular disease attributed to high BMI among young adults varied by region, country, gender, and Socio-demographic index (SDI). The greater burden of cardiovascular disease among young adults in low - and middle-income countries may be linked to unhealthy diets, health awareness, and lifestyles among young adults in low - and middle-income countries. Given the potential for improvement in high BMI, initiatives targeting this risk factor could significantly reduce the burden of CVD. Thus, prioritizing cost-effective policies and interventions is urgently needed.

Indexed as

Cardiovascular diseaseGlobalHigh body mass indexYoung adults

Identifiers

PMID40978299
PMCPMC12445712

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.