Evidence map›Paper›PMID 40978156›Full record

ArticleFrontiers in oral health2025

Influence of species composition and cultivation condition on peri-implant biofilm dysbiosis

Nils Heine, Kristina Bittroff, Szymon P Szafrański, Maya Duitscher, Wiebke Behrens, Clarissa Vollmer, Carina Mikolai, Nadine Kommerein, Nicolas Debener, Katharina Frings and 6 more

Abstract read
In one paragraph

Article in Frontiers in oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Nils HeineDepartment of Dental Prosthetics and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.
Kristina BittroffDepartment of Dental Prosthetics and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.
Szymon P SzafrańskiDepartment of Dental Prosthetics and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.
Maya DuitscherDepartment of Dental Prosthetics and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.
Wiebke BehrensDepartment of Dental Prosthetics and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.
Clarissa VollmerDepartment of Dental Prosthetics and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.
Carina MikolaiDepartment of Dental Prosthetics and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.
Nadine KommereinDepartment of Dental Prosthetics and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.
Nicolas DebenerInstitute of Technical Chemistry, Leibniz University Hannover, Hannover, Germany.
Katharina FringsLower Saxony Center for Biomedical Technology, Implant Research and Development (NIFE), Hannover, Germany.
Alexander HeisterkampLower Saxony Center for Biomedical Technology, Implant Research and Development (NIFE), Hannover, Germany.
Thomas ScheperLower Saxony Center for Biomedical Technology, Implant Research and Development (NIFE), Hannover, Germany.
Maria L Torres-MapaLower Saxony Center for Biomedical Technology, Implant Research and Development (NIFE), Hannover, Germany.
Janina BahnemannInstitute of Physics, University of Augsburg, Augsburg, Germany.
Meike Stiesch *Department of Dental Prosthetics and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.
Katharina Doll-Nikutta *Department of Dental Prosthetics and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Changes in bacterial species composition within oral biofilms, known as biofilm dysbiosis, are associated with the development of severe oral diseases. To better understand this process and help establish early detection systems, models are needed which replicate oral biofilm dysbiosis Methods: For this purpose, the present study cultivated two different combinations of oral commensal and pathogenic strains - Results: Biofilm growth and composition were strongly influenced by bacterial species selection, and to a more minor extent, by cultivation conditions. Within the model containing Conclusion: Within the present study, different

Indexed as

dental implantsdental plaquedynamic cultivationdysbiosismicrobiological techniques

Identifiers

PMID40978156
PMCPMC12443849

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.