Evidence map›Paper›PMID 40978131›Full record

ArticleJBMR plus2025

Effective management of pregnancy- and lactation-associated osteoporosis using romosozumab: a clinical case report.

Atsushi Goshima, Hideki Tsuboi, Takashi Kaito, Motoki Iwasaki

Abstract readCase Reports
In one paragraph

Article in JBMR plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Atsushi GoshimaDepartment of Orthopaedic Surgery, Osaka Rosai Hospital, Sakai 591-8025, Japan.ORCID https://orcid.org/0000-0002-0729-668X
Hideki TsuboiDepartment of Orthopaedic Surgery, Osaka Rosai Hospital, Sakai 591-8025, Japan.
Takashi KaitoDepartment of Orthopaedic Surgery, Osaka Rosai Hospital, Sakai 591-8025, Japan.
Motoki IwasakiDepartment of Orthopaedic Surgery, Osaka Rosai Hospital, Sakai 591-8025, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy- and lactation-related osteoporosis (PLO) is a rare condition characterized by reduced bone density and increased fracture risk during late pregnancy or early postpartum. Because of its rarity, no well-established treatment exists for PLO. Here, we report a case demonstrating significant improvements in bone density and the absence of new fractures after 12 mo of romosozumab (ROMO) treatment following weaning. This report suggests that ROMO could effectively increase bone density and reduce fracture risk in patients with PLO.

Indexed as

breastfeedingfractureosteoporosispregnancyromosozumab

Identifiers

PMID40978131
PMCPMC12448788

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.