Evidence map›Paper›PMID 40978057›Full record

ArticleFrontiers in oncology2025

Application of contrast-enhanced ultrasound for extradigital glomus tumor in the thigh: a case report.

Guangyuan Dai, Jiawen Fang, Shengmin Zhang

Abstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Guangyuan DaiDepartment of Ultrasound Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, China.
Jiawen FangDepartment of General Practice, Baiyun Community Health Service Center, Ningbo, China.
Shengmin ZhangDepartment of Ultrasound Medicine, The First Affiliated Hospital of Ningbo University, Ningbo, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glomus tumors (GTs) are rare neoplasms, classically presenting as subungual lesions with pathognomonic triad of severe paroxysmal pain triggered by cold, pressure, or touch. Extradigital glomus tumors (EGTs) pose significant diagnostic challenges due to their anatomical atypicality and frequently ambiguous clinical manifestations. Ultrasonography remains the primary imaging modality for evaluating soft tissue masses. In the diagnostic assessment of GTs by sonographers, the identification predominantly relies on characteristic clinical presentations combined with the demonstration of intratumoral hypervascularity through color Doppler imaging, as grayscale ultrasound features exhibit nonspecific characteristics. However, conventional ultrasonography encounters significant diagnostic challenges in EGTs with atypical clinical presentations and deep-seated locations, primarily due to the markedly reduced sensitivity of color Doppler in assessing blood flow within deep soft tissue lesions. In contrast, contrast-enhanced ultrasound (CEUS) allows dynamic visualization of microvascular perfusion patterns, enabling precise evaluation of intratumoral hemodynamic characteristics. This technique may assist in enhancing diagnostic accuracy and guiding targeted biopsies. We report a case of a 56-year-old man with a 4-year history of drug-resistant left thigh pain. CEUS revealed a 21-mm intramuscular mass exhibiting rapid heterogeneous enhancement followed by rapid washout, suggesting hypervascularity. Histopathology confirmed a glomus tumor of uncertain malignant potential. This case highlights the clinical and imaging characteristics of EGTs, providing clinicians with a comprehensive understanding of this rare entity.

Indexed as

case reportcontrast-enhanced ultrasoundextradigital glomus tumors (EGTs)imaging manifestationsultrasound

Identifiers

PMID40978057
PMCPMC12444763

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