ArticleFrontiers in nutrition2025
Prognostic risk factors in upper gastrointestinal perforation: the role of body composition parameters.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Development and validation of a CT-based body composition model for predicting adverse outcomes in small bowel obstruction.Frontiers in medicine · 2026Article
- Postoperative enteral nutrition timing and risk variation in elderly patients with perforated peptic ulcer.Frontiers in nutrition · 2026Article
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Authors and funding
6 authors.
Funding
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Abstract
Background: Despite medical advances, the prognosis for upper gastrointestinal perforation remained poor. The aim of our study was to identify predictors of adverse outcomes. Methods: We retrospectively analyzed laboratory data from patients with upper gastrointestinal perforation at the First Affiliated Hospital of Wenzhou Medical University (January 2021-December 2023), categorizing them according to septic shock, intensive care unit (ICU) admission, and postoperative complications. Results: Univariate and multivariate analyses of 200 patients with upper gastrointestinal perforation identified predictors of a poor prognosis: low muscle reserve (OR = 3.82, 95% CI 1.36-10.71, Conclusion: Our research found that the following factors were prognostic for upper gastrointestinal perforation: low muscle reserve, high VFA, PLR, sex, PT, D-dimer levels, surgical approach, WBC count, and perforation size.
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