Evidence map›Paper›PMID 40977979›Full record

ReviewFrontiers in nutrition2025

A blueprint for vitamin D fortification in sugar: stability and health impact.

Hardinsyah Hardinsyah, Rahmawati Rahmawati, Ahmad Sulaeman, Fahrul Nurkolis

Abstract readReview
In one paragraph

Review in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hardinsyah HardinsyahDepartment of Community Nutrition, Faculty of Human Ecology, IPB University, Bogor, Indonesia.
Rahmawati RahmawatiFood Technology Program, Sahid University, Jakarta Selatan, Indonesia.
Ahmad SulaemanDepartment of Community Nutrition, Faculty of Human Ecology, IPB University, Bogor, Indonesia.
Fahrul NurkolisState Islamic University of Sunan Kalijaga (UIN Sunan Kalijaga), Yogyakarta, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D deficiency is a global health concern, and fortifying widely consumed staples offers a scalable solution. Granulated sugar, accessible across socio-economic groups, shows promise as a novel vehicle for cholecalciferol delivery. Evidence indicates that vitamin D3 stability can be maintained through encapsulation and protective packaging, with over 90% potency retained under proper storage. Fortified sugar demonstrates good bioavailability, achieving absorption comparable to dairy products, and could increase serum 25(OH)D by 10-20 nmol/L at the population level. While offering low-cost impact, fortification requires careful dosing, quality control, and public education to mitigate risks of hypervitaminosis and prevent misperceptions that sugar itself is a health food.

Indexed as

25-hydroxyvitamin Dfood fortificationgranulated sugarhealthstabilityvitamin D

Identifiers

PMID40977979
PMCPMC12446249

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.