ArticlePlastic and reconstructive surgery. Global open2025
A Prospective Study of the Impact of Lymphatic Venous Anastomosis as a Treatment for Lymphedema.
Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Background: Lymphedema is managed using conservative modalities, which are most effective in early stages. Surgical interventions, such as lymphaticovenous anastomosis (LVA), are becoming popular as a method to augment conservative modalities. Despite a growing body of evidence demonstrating surgical effectiveness, prospective studies using validated measures and patient-reported outcomes are needed to further evaluate the impact of LVA. This prospective study evaluated the effect of LVA on limb volume, quality of life, and psychosocial well-being. Methods: Adults with stage 1-2 lymphedema undergoing LVA between January 2020 and December 2023 were included. All participants underwent 2 weeks of preoperative bandaging followed by lymphaticovenous anastomoses. Postoperative bandaging was administered for 6 weeks. Excess limb volume, lymphedema-specific quality of life, generalized anxiety (Generalized Anxiety Disorder-7), depressive symptoms (Patient Health Questionnaire-8), and lymphedema symptom intensity and distress were measured preoperatively and 6 weeks postoperatively. Qualitative semistructured interviews were also undertaken to contextualize findings. Results: Quantitative results indicated a modest reduction in percentage excess limb volume (median [interquartile range IQR], -4.40% [IQR, -12.20% to -1.50%], Conclusions: Our findings indicated modest improvements in percentage excess limb volume and overall quality of life after LVA. We therefore outlined several practice recommendations for the surgical care of lymphedema to improve surgical and postoperative management.
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