Evidence map›Paper›PMID 40977857›Full record

ArticleFrontiers in human neuroscience2025

Impact of transcutaneous auricular vagus nerve stimulation (taVNS) on cognitive flexibility as a function of task complexity.

Patricio Mena-Chamorro, Tomás Espinoza-Palavicino, Mauricio Barramuño-Medina, Tatiana Romero-Arias, Germán Gálvez-García

Abstract read
In one paragraph

Article in Frontiers in human neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Patricio Mena-ChamorroDepartamento de Psicología, Universidad de La Frontera, Temuco, Chile.
Tomás Espinoza-PalavicinoDepartamento de Psicología, Universidad de La Frontera, Temuco, Chile.
Mauricio Barramuño-MedinaPrograma de Kinesiología, Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Temuco, Chile.
Tatiana Romero-AriasFacultad de Ciencias de la Salud, Universidad Europea de Canarias, La Orotava, Spain.
Germán Gálvez-GarcíaDepartamento de Psicología, Universidad de La Frontera, Temuco, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to evaluate the effect of transcutaneous auricular vagus nerve stimulation (taVNS) on cognitive flexibility under different levels of task complexity. The hypothesis was that taVNS would enhance cognitive flexibility more effectively under demanding task conditions. Method: A within-subject design was used, involving 24 healthy adults who completed a Dimensional Change Card Sorting task combined with an auditory task of varying difficulty levels (low, medium, high). Participants underwent both active and sham taVNS conditions while performing the tasks. The complexity of the auditory task served to reduce cognitive resources available for the cognitive flexibility task, allowing an assessment of how taVNS modulates cognitive flexibility under different task difficulty conditions. Results: The results show that switch costs in the Dimensional Change Card Sorting task increase with task difficulty. In addition, active taVNS reduced switch costs significantly in the high complexity condition, while no differences were observed in the low and medium complexity conditions. This indicates that taVNS is particularly effective in conditions of higher cognitive demand. Conclusion: The findings suggest that taVNS enhances cognitive flexibility, especially in more complex tasks, providing a better understanding of the effects of taVNS on cognitive control.

Indexed as

cognitive flexibilityconcurrent auditory taskswitchingtask difficultytranscutaneous auricular vagus nerve stimulation

Identifiers

PMID40977857
PMCPMC12445146

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.