Evidence map›Paper›PMID 40977656›Full record

ArticleWorld journal of gastrointestinal oncology2025

Study of serum tumor markers in the early diagnosis of pancreatic cancer.

Qian-Xi Deng, Xue-Li Tang, Guo-Jun Yuan, Qin Jian, Xian-Hong Chen, Lin-Ju Wu

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Article in World journal of gastrointestinal oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Qian-Xi DengDepartment of Gastroenterology, The Third Hospital of Mianyang (Sichuan Mental Health Center), Mianyang 621000, Sichuan Province, China.
Xue-Li TangDepartment of Science and Technology, The Third Hospital of Mianyang (Sichuan Mental Health Center), Mianyang 621000, Sichuan Province, China.
Guo-Jun YuanDepartment of Gastroenterology, The Third Hospital of Mianyang (Sichuan Mental Health Center), Mianyang 621000, Sichuan Province, China.
Qin JianDepartment of Gastroenterology, The Third Hospital of Mianyang (Sichuan Mental Health Center), Mianyang 621000, Sichuan Province, China.
Xian-Hong ChenDepartment of Gastroenterology, The People's Hospital of Longchang, Neijiang 642150, Sichuan Province, China.
Lin-Ju WuDepartment of Anesthesiology, The Third Hospital of Mianyang (Sichuan Mental Health Center), Mianyang 621000, Sichuan Province, China. wulinju2149@mysyy.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPancreatic cancer is a highly aggressive malignancy with a dismal prognosis, primarily due to its late diagnosis. Current gold-standard diagnostic methods, such as tissue histopathological examination, are invasive and carry risks of complications (

aimTo explore the application value of serum tumor markers (CA-19-9, CEA) and serum sICAM-1 and CHI3 L1 in the early diagnosis of pancreatic cancer.

methodsFrom October 2021 to October 2024, 51 patients with pancreatic cancer were selected for the pancreatic cancer group, and 51 healthy examinees were selected for the healthy group during the same period. The value of serum tumor markers in combination with serum sICAM-1 and CHI3 L1 for the early diagnosis of pancreatic cancer was assessed.

resultsComparison of age, gender, body mass index, and drinking and smoking histories between the two groups was not statistically significant (

conclusionThe combined detection of serum tumor markers with serum sICAM-1 and serum CHI3 L1 can significantly improve the accuracy and sensitivity of the diagnosis of pancreatic cancer and its different stages.

Indexed as

Carbohydrate antigen 19-9Carcinoembryonic antigenChitinase-3-like protein 1Diagnostic valuePancreatic cancerSerum tumor markersSoluble intercellular adhesion molecule-1

Identifiers

PMID40977656
PMCPMC12444315

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