Evidence map›Paper›PMID 40977633›Full record

SynthesisDiagnostic and interventional radiology (Ankara, Turkey)2026

Magnetic resonance T1ρ relaxation in patients with liver fibrosis: a systematic review and meta-analysis.

Xiaoyu Liu, Yinzhong Wang, Caihua Xu, Yixiang Li, Junqiang Lei

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Diagnostic and interventional radiology (Ankara, Turkey), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaoyu LiuLanzhou University, Department of First Clinical Medical College, Lanzhou, China.ORCID 0009-0004-4603-7682
Yinzhong WangFirst Hospital of Lanzhou University, Department of Radiology, Lanzhou, China.ORCID 0000-0003-2208-4324
Caihua XuLanzhou University School of Basic Medical Sciences, Evidence-Based Medicine Center, Lanzhou, China.ORCID 0000-0001-5054-5875
Yixiang LiLanzhou University, Department of First Clinical Medical College, Lanzhou, China.ORCID 0000-0003-0640-149X
Junqiang LeiLanzhou University, Department of First Clinical Medical College, Lanzhou, China.ORCID 0000-0002-7632-1922

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to evaluate the diagnostic performance of T1ρ relaxation in distinguishing patients with liver fibrosis (LF) from those without.

methodsA systematic review was conducted using PubMed, EMBASE, Cochrane, and Web of Science databases up to February 2025 to identify studies assessing T1ρ for LF diagnosis.

resultsEleven studies involving 792 patients were included. T1ρ values were significantly higher in cirrhotic versus normal livers [weighted mean difference (WMD): 6.69,

conclusionT1ρ relaxation differentiates high-grade LF from normal liver tissue. CLINICAL SIGNIFICANCE: As a non-invasive imaging technique, T1ρ shows potential for use in the diagnosis and follow-up of LF and to optimize the assessment and management of chronic liver disease.

Indexed as

Liver CirrhosisMagnetic Resonance ImagingHumansLivercirrhosisimaging biomarkerLiver fibrosismeta-analysisT1ρ relaxation

Identifiers

PMID40977633
PMCPMC12766347

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.