Evidence map›Paper›PMID 40977602›Full record

ArticleEnvironmental science & technology2025

Ozonation of Pharmaceuticals and Their Human Metabolites in Wastewater─Insights from Laboratory Experiments and Field Data.

Corina Meyer, Pia M Kronsbein, Valentin Rougé, Urs von Gunten, Christa S McArdell, Juliane Hollender

Abstract read
In one paragraph

Article in Environmental science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Corina MeyerEawag: Swiss Federal Institute of Aquatic Science and Technology, Ueberlandstrasse 133, 8600 Duebendorf, Switzerland.ORCID 0000-0002-4593-8575
Pia M KronsbeinEawag: Swiss Federal Institute of Aquatic Science and Technology, Ueberlandstrasse 133, 8600 Duebendorf, Switzerland.
Valentin RougéEawag: Swiss Federal Institute of Aquatic Science and Technology, Ueberlandstrasse 133, 8600 Duebendorf, Switzerland.ORCID 0000-0002-6452-2209
Urs von GuntenEawag: Swiss Federal Institute of Aquatic Science and Technology, Ueberlandstrasse 133, 8600 Duebendorf, Switzerland.ORCID 0000-0001-6852-8977
Christa S McArdellEawag: Swiss Federal Institute of Aquatic Science and Technology, Ueberlandstrasse 133, 8600 Duebendorf, Switzerland.ORCID 0000-0002-5251-7541
Juliane HollenderEawag: Swiss Federal Institute of Aquatic Science and Technology, Ueberlandstrasse 133, 8600 Duebendorf, Switzerland.ORCID 0000-0002-4660-274X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pharmaceuticals and their human metabolites are contaminants of emerging concern in aquatic environments. While monitoring usually targets parent compounds, metabolites, often excreted at higher loads, are largely overlooked. This study investigates the behavior of both during wastewater treatment, focusing on ozonation as an advanced treatment step. Second-order rate constants for reactions of 87 parent compounds and 130 metabolites with ozone were determined using a multicompound competition kinetics method, enabling exploration of functional group-specific reactivity trends. Aromatic hydroxylation generally increased ozone reactivity (up to 5 orders of magnitude), whereas

Indexed as

OzoneWastewaterHumansPharmaceutical PreparationsWater Pollutants, ChemicalOzonePharmaceutical PreparationsWastewaterWater Pollutants, ChemicalHuman metabolitesMulticompound competition kineticsOzonationPharmaceuticalsWastewater treatment

Identifiers

PMID40977602
PMCPMC12490022

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.