Evidence map›Paper›PMID 40977370›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2025

A scalable framework for benchmark embedding models in semantic health-care tasks.

Shelly Soffer, Mahmud Omar, Moran Gendler, Benjamin S Glicksberg, Patricia Kovatch, Orly Efros, Robert Freeman, Alexander W Charney, Girish N Nadkarni, Eyal Klang

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shelly SofferInstitute of Hematology, Davidoff Cancer Center, Rabin Medical Center, Petah Tikva, 49100, Israel.
Mahmud OmarWindreich Department of AI and Human Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.ORCID 0009-0001-0438-0827
Moran GendlerAzrieli Faculty of Medicine, Bar-Ilan University, Safed, 1311502, Israel.ORCID 0009-0004-7789-3801
Benjamin S GlicksbergWindreich Department of AI and Human Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.
Patricia KovatchDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.
Orly EfrosGray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, 6997801, Israel.ORCID 0000-0002-6024-9110
Robert FreemanWindreich Department of AI and Human Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.ORCID 0000-0003-4946-6533
Alexander W CharneyWindreich Department of AI and Human Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.
Girish N NadkarniWindreich Department of AI and Human Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.
Eyal KlangWindreich Department of AI and Human Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.

Funding

Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
Clinical and Translational Science UL1TR004419NCATS NIH HHS UL1 TR004419
6 · The paper itself

Abstract

objectivesText embeddings are promising for semantic tasks, such as retrieval augmented generation (RAG). However, their application in health care is underexplored due to a lack of benchmarking methods. We introduce a scalable benchmarking method to test embeddings for health-care semantic tasks. MATERIALS AND

methodsWe evaluated 39 embedding models across 7 medical semantic similarity tasks using diverse datasets. These datasets comprised real-world patient data (from the Mount Sinai Health System and MIMIC IV), biomedical texts from PubMed, and synthetic data generated with Llama-3-70b. We first assessed semantic textual similarity (STS) by correlating the model-generated similarity scores with noise levels using Spearman rank correlation. We then reframed the same tasks as retrieval problems, evaluated by mean reciprocal rank and recall at k.

resultsIn total, evaluating 2000 text pairs per 7 tasks for STS and retrieval yielded 3.28 million model assessments. Larger models (>7b parameters), such as those based on Mistral-7b and Gemma-2-9b, consistently performed well, especially in long-context tasks. The NV-Embed-v1 model (7b parameters), although top in short tasks, underperformed in long tasks. For short tasks, smaller models such as b1ade-embed (335M parameters) performed on-par to the larger models. For long retrieval tasks, the larger models significantly outperformed the smaller ones. DISCUSSION: The proposed benchmarking framework demonstrates scalability and flexibility, offering a structured approach to guide the selection of embedding models for a wide range of health-care tasks.

conclusionBy matching the appropriate model with the task, the framework enables more effective deployment of embedding models, enhancing critical applications such as semantic search and retrieval-augmented generation (RAG).

Indexed as

BenchmarkingInformation Storage and RetrievalNatural Language ProcessingSemanticsHumansartificial intelligencelarge language modelsmedical NLP tools

Identifiers

PMID40977370
PMCPMC12646376

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.