SynthesisClinical and experimental dental research2025
Effects of Drug Administration on Postoperative Pain in Orthognathic Surgery: A Systematic Review.
Synthesis in Clinical and experimental dental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Influence of vertical growth pattern on masseter muscle morphology: evidence from cephalometric and ultrasound assessment in eighteen growing subjects.Frontiers in dental medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
objectivesThis systematic review aims to offer indications on how drug administration affects postoperative pain in patients undergoing orthognathic surgery. MATERIAL AND
methodsWe searched Pubmed, Scopus, and Web of Science for articles pertaining to our research topic. The search strategy was created by combining terms associated with our review's goal, which is to ascertain whether drugs used before, during, and after surgery help lessen postoperative pain. The keywords used were "orthodontic surgery AND postoperative pain." Inclusion criteria used to select articles were human subjects only, open-access studies, clinical and randomized controlled trials, English language, and studies published no more than 10 years before the current edition. Exclusion conditions such as eta-analyses, systematic reviews, off-topics, abstracts, posters, and public trials were excluded.
resultsThirteen randomized control trials and one comparative study comprised the design of the chosen research. The studies show that administering a certain drug in comparison to another can lessen the severity of postoperative sequelae.
conclusionsA multimodal approach is needed to alleviate post-discomfort after orthognathic surgery. Medication given before surgery can lessen discomfort and the need for opioids. Pain intensity can be decreased, and early opioid tolerance can be avoided with intraoperative treatments. Non-steroidal anti-inflammatory drugs and iontophoresis-based transdermal medication administration are other alternatives.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.