Evidence map›Paper›PMID 40976894›Full record

ArticleCurrent neuropharmacology2026

An Efficient Neuro-framework for Brain Tumor Classification Using a CNN-based Self-supervised Learning Approach with Genetic Optimizations.

Paripelli Ravali, Pundru Chandra Shaker Reddy, Pappula Praveen

Abstract read
In one paragraph

Article in Current neuropharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Paripelli RavaliSchool of Computer Science and Artificial Intelligence, SR University, Warangal, Telangana, India.
Pundru Chandra Shaker ReddySchool of Computer Science and Artificial Intelligence, SR University, Warangal, Telangana, India.
Pappula PraveenSchool of Computer Science and Artificial Intelligence, SR University, Warangal, Telangana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAccurate and non-invasive grading of glioma brain tumors from MRI scans is challenging due to limited labeled data and the complexity of clinical evaluation. This study aims to develop a robust and efficient deep learning framework for improved glioma classification using MRI images.

methodsA multi-stage framework is proposed, starting with SimCLR-based self-supervised learning for representation learning without labels, followed by Deep Embedded Clustering to extract and group features effectively. EfficientNet-B7 is used for initial classification due to its parameter efficiency. A weighted ensemble of EfficientNet-B7, ResNet-50, and DenseNet-121 is employed for the final classification. Hyperparameters are fine-tuned using a Differential Evolution-optimized Genetic Algorithm to enhance accuracy and training efficiency.

resultsEfficientNet-B7 achieved approximately 88-90% classification accuracy. The weighted ensemble improved this to approximately 93%. Genetic optimization further enhanced accuracy by 3-5% and reduced training time by 15%. DISCUSSION: The framework overcomes data scarcity and limited feature extraction issues in traditional CNNs. The combination of self-supervised learning, clustering, ensemble modeling, and evolutionary optimization provides improved performance and robustness, though it requires significant computational resources and further clinical validation.

conclusionThe proposed framework offers an accurate and scalable solution for glioma classification from MRI images. It supports faster, more reliable clinical decision-making and holds promise for real-world diagnostic applications.

Indexed as

Brain NeoplasmsGliomaSupervised Machine LearningClassification AlgorithmsClustering AlgorithmsConvolutional Neural NetworksGenetic AlgorithmsHumansMagnetic Resonance Imagingdeep learninggenetic optimizationsGlioma classificationMRI-Imagingneurobiologyself-supervised learning

Identifiers

PMID40976894
PMCPMC13647694

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.