ReviewCurrent aging science2026
Nanotechnology-Based Approaches for Combating Skin Aging: A Comprehensive Review.
Review in Current aging science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Nanotechnologies for Skin Drug Delivery: Polymeric, Bio-Based, and Hybrid Nanocarriers with Clinical and Translational Perspectives.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Advances in polyphenol-based strategies for musculoskeletal recovery and exercise rehabilitation in cancer: Mechanistic insights into Wnt/β-catenin and PI3K/Akt signaling pathways and inflammatory markers.Frontiers in oncology · 2026Review
- A State-of-the-Art Overview on (Epi)Genomics and Personalized Skin Rejuvenating Strategies.Pharmaceutics · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe aging of skin is a multifaceted biological phenomenon influenced by both intrinsic and extrinsic factors. As awareness among the public increases, there is a growing interest in natural ingredients and cutting-edge cosmetic solutions that enhance skin appearance and mitigate the aging process. Nanotechnology has emerged as a significant field within cosmeceuticals, providing innovative solutions that overcome the limitations of conventional cosmetic formulations by enhancing delivery, stability, and targeted efficacy.
methodsThis review synthesized contemporary research on nanotechnology-driven approaches utilized in anti-aging skincare. A comprehensive search of scientific databases, including Pub- Med, Scopus, and Google Scholar, was performed to identify research articles and review papers using keywords, such as "nanotechnology", "skin aging", "anti-aging cosmetics", "nanocarriers", and "bioactive compounds". The emphasis was placed on studies that highlight nanosized delivery systems and their mechanisms in addressing issues related to skin aging.
resultsBioactive compounds targeting anti-aging, such as antioxidants (including ascorbic acid, alpha-tocopherol, lipoic acid, and coenzyme Q10) and plant extracts (such as green tea, turmeric, and resveratrol), were successfully integrated into nanocarrier systems. These systems, comprising lipid nanoparticles, polymeric carriers, nanoemulsions, dendrimers, and fullerenes, demonstrate improved penetration, stability, and controlled release compared to traditional formulations, thereby enhancing the effectiveness of active ingredients in addressing signs of aging. DISCUSSION: Nanotechnology-driven skincare has demonstrated enhanced delivery, stability, and bioavailability of anti-aging compounds, addressing limitations of conventional formulations. Nanosized carriers improve penetration and controlled release, optimizing the functional benefits of antioxidants and botanical extracts. However, concerns related to safety, toxicity, and regulatory compliance require further investigation. Sustainable nanocarrier development and interdisciplinary collaborations will be essential for balancing efficacy with safety. Continued research will be crucial to establishing standardized guidelines and ensuring the successful commercialization of nano-based anti-aging cosmetics.
conclusionNanotechnology presents significant potential for the development of effective antiaging cosmetic products. The use of nanosized delivery systems significantly enhances the efficacy of active ingredients, providing a viable alternative to traditional formulations. Nonetheless, challenges related to safety, toxicity, regulatory compliance, and long-term clinical application must be addressed in future research to facilitate the successful commercialization of these products. Additionally, future investigations should consider sustainable practices.
Indexed as
Identifiers
40976893What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.