Evidence map›Paper›PMID 40976481›Full record

Observational studyThe Journal of nutrition2025

The Effect of Habitual Sleep Duration on Weight Loss during a Behavioral Weight Loss Intervention in a Mediterranean Population.

María Rodríguez-Martín, Lukasz Szczerbinski, Marta Garaulet, Hassan S Dashti

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in The Journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02829619 (Meal Timing, Genetics and Weight Loss in a Mediterranean Population), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02829619 recruitingnot on this map

Meal Timing, Genetics and Weight Loss in a Mediterranean Population

TypeobservationalSponsorUniversidad de MurciaRan2008 to 2032Enrolled5,788ConditionsObesity
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Optimal nap timing and body mass index: beyond duration.Journal of translational medicine · 2026
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

María Rodríguez-MartínDepartment of Physiology, University of Murcia, Avenida Buenavista 32, LAIB Building, El Palmar, 30120 Murcia, Spain; Nutrition Group of Research, Biomedical Research Institute of Murcia Pascual Parrilla-IMIB, 30120 Murcia, Spain.
Lukasz SzczerbinskiDepartment of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland; Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, United States; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, United States; Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.
Marta GarauletDepartment of Physiology, University of Murcia, Avenida Buenavista 32, LAIB Building, El Palmar, 30120 Murcia, Spain; Nutrition Group of Research, Biomedical Research Institute of Murcia Pascual Parrilla-IMIB, 30120 Murcia, Spain; Medical Chronobiology Program, Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, United States; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, United States. Electronic address: garaulet@um.es.
Hassan S DashtiDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, United States; Division of Sleep Medicine, Harvard Medical School, Boston, MA, United States; Division of Nutrition, Harvard Medical School, Boston, MA, United States. Electronic address: hassan.dashti@mgh.harvard.edu.

Funding

The impact of overnight nutrition support on sleep and circadian rhythm disruption in the ICUR00HL153795 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI DASHTI, HASSAN S. · 2023 to 2025
$747k
NHLBI NIH HHS R00 HL153795
6 · The paper itself

Abstract

backgroundSleep duration affects metabolic health and regulates appetite, but its role in behavioral weight loss interventions remains unclear as prior studies are limited by small sample sizes, cross-sectional designs, and inconsistent findings.

objectivesThis study aims to examine the associations between nighttime sleep duration and weight loss during a behavioral intervention in adults with overweight or obesity in Spain.

methodsThis secondary analysis included adults with overweight or obesity from the Obesity, Nutrigenetics, Timing, and Mediterranean study, a 25-wk behavioral weight loss program. Participants self-reported sleep duration at enrollment and were categorized as short (<7 h), recommended (7-8 h), or long (>8 h) sleepers. Outcomes included percentage of weight loss, clinically meaningful or successful weight loss (≥5% of initial body weight), rate of weight loss (high/rapid rate ≥0.53 kg/wk), and attrition. Associations were examined using logistic regression and linear mixed-effects models adjusted for age, sex, baseline weight, intervention duration, and clinic site.

resultsAmong 3628 participants (mean age 41.2 ± 14.1 y; 77.6% women), 23.7% reported sleeping >8 h, 60.9% reported sleeping 7-8 h, and 15.4% reported sleeping <7 h per night. Long sleepers had significantly lower average weight loss (7.42% of baseline weight) compared with recommended sleepers (7.90%, P = 0.015). Long sleep was associated with 21% lower odds of achieving a weight loss ≥5% of baseline weight [odds ratio (OR): 0.79; 95% confidence interval (CI): 0.66, 0.96], 25% lower odds of rapid weight loss (OR: 0.75; 95% CI: 0.63, 0.89), and 21% higher odds of attrition (OR: 1.21; 95% CI: 1.03, 1.43) compared with recommended sleep. No significant associations were observed for short sleepers. Linear mixed-effects models indicated lower weight loss among long sleepers [β: 0.099; standard error (SE): 0.040; P = 0.015], but not for short sleepers (β: -0.031; SE: 0.048; P = 0.514).

conclusionsHabitual long sleep duration is associated with reduced weight loss success and increased risk of attrition in a behavioral weight loss intervention. This trial was registered at clinicaltrials.gov as NCT02829619.

Indexed as

Behavior TherapyObesityOverweightSleepWeight LossWeight Reduction ProgramsAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedSleep DurationSpainTime Factorsattritionbehavioral interventionlong sleepobesitysleep durationweight loss

Identifiers

PMID40976481
PMCPMC13320611

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.