Trial reportBJOG : an international journal of obstetrics and gynaecology2026
Exercise in Pregnancy and Risk of Postpartum Depression: A Randomised Controlled Trial.
Trial report in BJOG : an international journal of obstetrics and gynaecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06355375 (Exercise in Pregnancy and Risk of Postpartum Depression), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exercise in Pregnancy and Risk of Postpartum Depression
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Isolated physical activity programs during pregnancy and postpartum: Meta-analysis of randomized trials with usual-care controls on depressive and anxiety symptoms.Archives of women's mental health · 2026Pooled it
- Exercise in pregnancy and maternal cardiovascular changes.BMC pregnancy and childbirth · 2026Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate whether regular aerobic exercise during pregnancy reduces the incidence of postpartum depression in women with low-risk singleton pregnancies.
designSingle-centre randomised controlled trial.
settingDepartment of Obstetrics and Gynaecology, University of Naples Federico II, Italy. POPULATION OR SAMPLE: A total of 398 women with low-risk singleton pregnancies enrolled during the first trimester of pregnancy.
methodsParticipants were randomly allocated in a 1:1 ratio to an exercise group or control group. The intervention consisted of a structured aerobic exercise programme (three 60-min sessions per week) from randomisation until 35 weeks' gestation, or earlier if delivery or obstetric complications occurred. The primary outcome was Edinburgh Postnatal Depression Scale (EPDS) score ≥ 12 3 months postpartum. Secondary outcomes included EPDS ≥ 9, clinical diagnosis of postpartum depression (DSM-V), and maternal/perinatal outcomes. Analyses were performed on an intention-to-treat basis, with relative risk (RR) and 95% confidence interval (CI) calculated.
main outcome measuresIncidence of postpartum depression, defined as EPDS ≥ 12 at 3 months postpartum.
resultsOf the 398 participants, 199 were randomised to the exercise group and 199 to the control group. Women in the exercise group had a significantly lower incidence of EPDS ≥ 12 and ≥ 9 at 3 months postpartum compared with controls, as well as lower mean EPDS scores. No significant differences in adverse maternal or perinatal outcomes were observed.
conclusionsRegular antenatal aerobic exercise significantly reduced the risk of postpartum depression, supporting its role as a preventive strategy in low-risk pregnancies.
trial registrationClinicaltrials.gov identifier: NCT06355375.
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