Evidence map›Paper›PMID 40975726›Full record

ArticleJournal of cancer survivorship : research and practice2025

Quality of life among non-metastatic breast cancer survivors in Botswana.

Rachel B Wagner, James R Wester, Bosa Motladiile, Isaac Nkele, Nkhabe Chinyepi, Gontse Tshisimogo, Peter Vuylsteke, Shahin Lockman, Scott Dryden-Peterson, Racquel E Kohler

Abstract read
In one paragraph

Article in Journal of cancer survivorship : research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rachel B WagnerCenter for Cancer Health Equity, Rutgers Cancer Institute, 120 Albany St, New Brunswick, NJ, 08901, USA.
James R WesterDepartment of Surgery, University of Pennsylvania, 3400 Spruce St, Philadelphia, PA, 19104, USA.
Bosa MotladiileBotswana Harvard Health Partnership, Plot No. 1836 North Ring Rd, Gaborone, Botswana.
Isaac NkeleBotswana Harvard Health Partnership, Plot No. 1836 North Ring Rd, Gaborone, Botswana.
Nkhabe ChinyepiDepartment of Surgery, University of Botswana, Plot 4775 Notwane Rd, Gaborone, Botswana.
Gontse TshisimogoBotswana Ministry of Health and Wellness, Plot 8WV5+J79, Nelson Mandela Dr, Gaborone, Botswana.
Peter VuylstekeDepartment of Internal Medicine, University of Botswana, Gaborone, Botswana.
Shahin LockmanBotswana Harvard Health Partnership, Plot No. 1836 North Ring Rd, Gaborone, Botswana.
Scott Dryden-PetersonBotswana Harvard Health Partnership, Plot No. 1836 North Ring Rd, Gaborone, Botswana.
Racquel E KohlerCenter for Cancer Health Equity, Rutgers Cancer Institute, 120 Albany St, New Brunswick, NJ, 08901, USA. kelly.kohler@rutgers.edu.

Funding

Partnership for Global Health Research Training Program (Renewal)-Supplement for OBSSR, NCI, NCI-AIDS and NIDCDD43TW010543 · FIC · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Wafaie W Fawzi, DAVIDSON HOWES HAMER · 2017 to 2026
$12.1M
Covid-19-related cervical cancer treatment interruption and role of neoadjuvant chemotherapyR01CA236546 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI DRYDEN-PETERSON, SCOTT · 2019 to 2023
$2.5M
Mentoring in Patient-Oriented HIV Research in the Era of Universal ARTK24AI131928 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI SHAHIN LOCKMAN · 2017 to 2026
$1.9M
Addressing HPV vaccination disparities through tailored messaging for hesitant familiesK22CA258675 · NCI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI KOHLER, RACQUEL ELIZABETH · 2022 to 2024
$660k
FIC NIH HHS D43 TW010543NCI NIH HHS R01 CA236546NIH HHS D43 TW010543NIH HHS K22CA258675NIH HHS K24AI131928NIH HHS P30CA006516-50S4
6 · The paper itself

Abstract

purposeThis study explored quality of life (QOL) experiences after non-metastatic breast cancer treatment, especially related to mastectomy, among survivors in Botswana.

methodsWe conducted 23 qualitative interviews in Setswana with survivors who were within 1-5 years of having a mastectomy from a nationwide cancer survivorship cohort. Physical and mental QOL, measured by SF-8, were also assessed. We translated, double-coded, and thematically analyzed transcripts according to QOL domains.

resultsOver half of participants were diagnosed with stage III disease; all received chemotherapy and mastectomy. Key aspects of physical, financial, psychological, and social QOL that were influenced by treatment included the following: (1) pain, mobility, and fatigue; (2) reduced work capacity and financial stress; (3) depression, anxiety, and body image; and (4) mixed social support due to stigma. We also identified structural factors that limited access to symptom management and support services, which affected multiple aspects of QOL.

conclusionsLong-term pain, mobility restrictions, and fatigue affected physical functioning, specifically regarding employment, which had an overall negative impact on household financial status. Though some survivors received informal support through social networks, access to symptom management, support services, and public assistance was limited. Implications for Cancer Survivors This study highlights multi-level challenges that affect QOL after mastectomy in Botswana. Interventions enhancing physical symptom management and improving psychosocial support services may improve QOL of survivors across sub-Saharan Africa.

Indexed as

Breast cancerMastectomyQuality of lifeSub-Saharan Africa

Identifiers

PMID40975726
PMCPMC13093326

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.