ArticleJournal of perinatology : official journal of the California Perinatal Association2026
Association of low shunt burden from PDA and adverse outcomes in premature infants.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- AI, machine learning, and adjudication of hemodynamically significant PDA in extremely premature infants.Pediatric research · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveCompare the incidence of death or adverse respiratory outcome in patients with low shunt burden from PDA to those with no PDA and evaluate secondary outcomes associated with PDA between groups. STUDY
designRetrospective cohort study of all infants born <30 weeks gestation from 8/2018 to 5/2023 with TNE in the first postnatal week. Two groups: no PDA burden and low PDA burden. Primary outcome was composite of death or adverse respiratory outcome.
results112 infants [no PDA (n = 69), low PDA burden (n = 43)] with mean gestational age and birth weight 27 ± 2 weeks and 1006 ± 310 g, respectively, were included. Baseline demographics were comparable with no difference in primary outcome (p = 0.2).
conclusionProlonged exposure to low-volume PDA shunt was not associated with increased risk of death or abnormal respiratory outcome. Findings highlight the importance of redefining eligibility criteria for PDA trials, based on adjudication of shunt volume, to limit enrollment to patients with moderate- to high-volume shunts.
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