Evidence map›Paper›PMID 40975053›Full record

ArticleCurrent biology : CB2025

A parent-of-origin effect on embryonic telomere elongation determines telomere length inheritance.

Hyuk-Joon Jeon, Mia T Levine, Michael A Lampson

Abstract read
In one paragraph

Article in Current biology : CB, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Hyuk-Joon JeonDepartment of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
Mia T LevineDepartment of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA; Penn Center for Genome Integrity, University of Pennsylvania, Philadelphia, PA 19104, USA; Epigenetics Institute, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: m.levine@sas.upenn.edu.
Michael A LampsonDepartment of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA; Penn Center for Genome Integrity, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: lampson@sas.upenn.edu.

Funding

Cell Biological mechanisms of centromere driveR35GM122475 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Michael Lampson · 2017 to 2026
$4.5M
Causes and functional consequences of chromatin evolutionR35GM124684 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Mia Tauna Levine · 2017 to 2026
$3.5M
Evolutionary innovation to preserve zygotic genome integrityR21HD102801 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI LAMPSON, MICHAEL, LEVINE, MIA TAUNA · 2020 to 2021
$446k
NICHD NIH HHS R21 HD102801NIGMS NIH HHS R35 GM122475NIGMS NIH HHS R35 GM124684
6 · The paper itself

Abstract

Telomeres are composed of specialized DNA, RNA, and proteins that interact to preserve the integrity of chromosome termini.

Indexed as

TelomereTelomere HomeostasisAnimalsEmbryo, MammalianFemaleMaleMiceMice, Inbred C57BLalternative lengthening of telomerespre-implantation embryotelomere length

Identifiers

PMID40975053
PMCPMC12743270

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.