Trial reportLasers in medical science2025
Effectiveness of photobiomodulation therapy as an adjunct to surface spinal stimulation and activity-based therapy in compressive cervical myelopathy: a parallel group, non-blinded randomized controlled trial.
Trial report in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To reverse the progression of compressive cervical myelopathy (CCM) by repairing injured nerve tissue, improving sensory integration, balance, disability, and quality of life (QoL) with Photobiomodulation Therapy (PBMT) as an adjunct to Surface Spinal Stimulation (SSS) and Activity-Based Therapy (ABT). Thirty-two individuals in the age group between, 20 and 65 years diagnosed with sub-acute CCM were recruited through purposive sampling method for the parallel non-blinded randomized controlled trial. Randomized using block randomization into experimental group and control group. As an adjunct to surface spinal stimulation and activity-based therapy and conventional physiotherapy in the control group, the experimental group received Photo-biomodulation therapy using Class IV LASER for 5 Sessions/week for 3 weeks. Assessed using, Hoffmann's-reflex, Modified-Clinical Testing for Sensory Integration and Balance (m-CTSIB), Japanese Orthopaedic Association Cervical Myelopathy Evaluation Questionnaire (JOACMEQ), and Neck Disability Index (NDI) at baseline, 7th day and 15th day in both the groups. Within-group differences were evaluated by using the Friedman test and the between-group differences in the outcome variables were evaluated by the Mann-Whitney U test. H-Amplitude at 15th day and JOACMEQ-QoL at 7th day demonstrated significant difference (p < 0.05) between the groups. Significant changes (p < 0.05) were observed within experimental group while compared to the control group in H-amplitude, m-CTSIB, JOACMEQ and NDI. Individuals with compressive cervical myelopathy receiving PBMT as an adjunct to SSS and ABT experienced significantly better outcomes (e.g., improved function, reduced pain, improved QOL) compared to those receiving only SSS and ABT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.