Evidence map›Paper›PMID 40974407›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2026

Baseline [

Xilan Yao, Lijing Wei, Hongrong Wang, Xiao Lei, Zheqin Wang, Shuang Yao, Jigang Yang

Abstract read
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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xilan YaoDepartment of Nuclear Medicine, Beijing Friendship Hospital of Capital Medical University, 95 Yong An Road, Xi Cheng District, Beijing, 100050, China.
Lijing WeiDepartment of Nuclear Medicine, Beijing Boren Hospital, Beijing, China.
Hongrong WangDepartment of Nuclear Medicine, Beijing Boren Hospital, Beijing, China.
Xiao LeiDepartment of Nuclear Medicine, Beijing Boren Hospital, Beijing, China.
Zheqin WangDepartment of Nuclear Medicine, Beijing Boren Hospital, Beijing, China.
Shuang YaoDepartment of Nuclear Medicine, Beijing Fengtai You'anmen Hospital, Beijing, China.
Jigang YangDepartment of Nuclear Medicine, Beijing Friendship Hospital of Capital Medical University, 95 Yong An Road, Xi Cheng District, Beijing, 100050, China. yangjigang@ccmu.edu.cn.ORCID 0000-0002-0538-7676

Funding

National Natural Science Foundation of China No: 82272034Natural Science Foundation of Beijing Municipality No:7232031
6 · The paper itself

Abstract

purposeThis study aimed to characterize the non-central nervous system extramedullary disease (non-CNS EMD) in patients with relapsed/refractory B-cell acute lymphoblastic leukemia (r/r B-ALL) and to evaluate the prognostic value of metabolic parameters derived from [

methodsPatients with r/r B-ALL who received chimeric antigen receptor (CAR)-T cell therapy and underwent [

resultsA total of 81 B-ALL patients were included in this study. The most frequently observed non-CNS EMD lesions involved the lymph node, spleen, and kidney. After a median follow-up time of 23.7 months, multivariate analysis identified hemoglobin (Hb) and SUVmax (with a cut-off value of 7.0) as independent prognostic factors for PFS and OS. Patients with abnormal Hb levels exhibited significantly shorter PFS and OS compared to those with normal Hb levels (median PFS: 13.5 months vs. not reached, P = 0.004; median OS: 48.0 months vs. not reached, P = 0.010). Similarly, patients with SUVmax above the threshold had significantly reduced PFS and OS compared to those below the threshold (median PFS: 9.1 months vs. not reached, P ≤ 0.001; median OS: 27.0 months vs. 50.8 months, P = 0.020).

conclusion[

Indexed as

Fluorodeoxyglucose F18Immunotherapy, AdoptivePositron Emission Tomography Computed TomographyPrecursor B-Cell Lymphoblastic Leukemia-LymphomaReceptors, Chimeric AntigenAdolescentAdultAgedChildFemaleHumansMaleMiddle AgedPrognosisRecurrenceRetrospective StudiesFluorodeoxyglucose F18Receptors, Chimeric AntigenAcute lymphoblastic leukemiaCAR-TExtramedullaryPET/CTPrognosis

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.