Evidence map›Paper›PMID 40974188›Full record

ArticleArtificial organs2026

Machine Learning-Based Prediction of Life-Threatening Complications During Hemodialysis in Hospitalized Patients With Poor General Conditions.

Naotaka Kato, Takeshi Goto, Tomoyuki Ohira, Hirotaka Kinoshita, Kugo Kurokawa, Kouhei Naganuma, Chikako Ohminato, Junko Ogasawara, Shingo Hatakeyama, Yoshihiro Sasaki and 2 more

Abstract read
In one paragraph

Article in Artificial organs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Naotaka KatoDepartment of Clinical Engineering, Hirosaki University School of Medicine and Hospital, Hirosaki, Japan.ORCID https://orcid.org/0009-0007-7038-2103
Takeshi GotoDepartment of Clinical Engineering, Hirosaki University School of Medicine and Hospital, Hirosaki, Japan.ORCID https://orcid.org/0000-0001-6975-8248
Tomoyuki OhiraDepartment of Clinical Engineering, Hirosaki University School of Medicine and Hospital, Hirosaki, Japan.
Hirotaka KinoshitaDepartment of Anesthesiology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Kugo KurokawaDepartment of Clinical Engineering, Hirosaki University School of Medicine and Hospital, Hirosaki, Japan.
Kouhei NaganumaDepartment of Clinical Engineering, Hirosaki University School of Medicine and Hospital, Hirosaki, Japan.
Chikako OhminatoDepartment of Clinical Engineering, Hirosaki University School of Medicine and Hospital, Hirosaki, Japan.
Junko OgasawaraDepartment of Clinical Engineering, Hirosaki University School of Medicine and Hospital, Hirosaki, Japan.
Shingo HatakeyamaDepartment of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.ORCID https://orcid.org/0000-0002-0026-4079
Yoshihiro SasakiDepartment of Medical Informatics, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Kazuyoshi HirotaDepartments of Perioperative Stress Management, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Chikara OhyamaDepartment of Advanced Transplant and Regenerative Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients undergoing hemodialysis (HD) face a significantly elevated risk of cardiovascular mortality, with sudden events during treatment posing a critical threat to survival. These risks are particularly pronounced in high-risk populations, such as patients recovering from cardiovascular surgery or those being treated for sepsis. Therefore, the development of effective preventive strategies is essential for improving patient outcomes. This study aimed to develop a machine learning model that uses pretreatment patient characteristics to predict sudden adverse events during HD and within 24 h after treatment in high-risk inpatients at acute care hospitals.

methodsHis retrospective study analyzed data from 739 patients who underwent HD at Hirosaki University Hospital between 2018 and 2021. Sudden events were defined as fatal arrhythmia, refractory intradialytic hypotension, or respiratory arrest. A logistic regression model was constructed using backward stepwise selection from 51 patient characteristics (demographic data, clinical parameters, laboratory data, and HD-related information).

resultsAmong the 739 patients, 17 (2.3%) experienced sudden events. The model identified 23 pre-HD covariates and achieved an area under the receiver operating characteristic curve (AUC) of 0.889. Key covariates included emergency hospitalization (present in 71% of patients with sudden events), recent surgery (76%), shorter HD history, elevated pre-HD heart rate, lower serum albumin levels, and higher C-reactive protein concentrations.

conclusionsOur model enables the early identification of high-risk inpatients receiving hemodialysis using pre-dialysis data, thereby supporting timely clinical interventions, optimized resource allocation, and improved patient safety.

Indexed as

Kidney Failure, ChronicMachine LearningRenal DialysisAgedFemaleHospitalizationHumansHypotensionMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk Factors

Identifiers

PMID40974188
PMCPMC12954476

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.