ReviewJournal of animal science and biotechnology2025
Silymarin as a feed additive in swine and poultry production: a comprehensive review.
Review in Journal of animal science and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Energy-sparing effect of oregano essential oil-lauric acid complex in broilers: Insights from serum metabolomics and 16S rRNA sequencing.Poultry science · 2026Article
- Effects ofAnimals : an open access journal from MDPI · 2026Article
- Redox Homeostasis in Poultry/Animal Production.Antioxidants (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The widespread ban on in-feed antibiotics in many regions has driven the search for natural alternatives to maintain health and production efficiency in swine and poultry. Phytogenic feed additives (PFAs) derived from herbs and plant extracts have emerged as promising candidates owing to their antioxidant, anti-inflammatory, and antimicrobial properties. Among these, silymarin-a flavonolignan complex extracted from milk thistle (Silybum marianum)-has attracted particular attention due to its hepatoprotective and growth-promoting activities. This review summarizes the chemical characteristics and mechanisms of action of silymarin/silybin. Also, evidence from both experimental and field studies shows that silymarin improves growth performance, nutrient digestibility, gut health, and reproductive outcomes. Advances in formulation technologies, such as micellization, have been addressed for improved bioavailability of silymarin. Despite these promising results, further long-term field studies and economic evaluations are needed to fully integrate silymarin into commercial animal production systems.
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Registered trials
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