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ReviewLasers in medical science2025

The most influential research in laser therapy for acne and acne scars: A bibliometric analysis.

Siddig Ibrahim Abdelwahab, Manal Mohamed Elhassan Taha, Abdullah Farasani, Saleh M Abdullah, Jobran M Moshi, Nizar A Khamjan, Ahmad Assiri, Saeed Alshahrani, Khaled A Sahli, Marwa Qadri and 1 more

Abstract readReview
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In one paragraph

Review in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Siddig Ibrahim AbdelwahabJazan University, Jazan, Saudi Arabia.
Manal Mohamed Elhassan TahaJazan University, Jazan, Saudi Arabia.
Abdullah FarasaniJazan University, Jazan, Saudi Arabia.
Saleh M AbdullahJazan University, Jazan, Saudi Arabia.
Jobran M MoshiJazan University, Jazan, Saudi Arabia.
Nizar A KhamjanJazan University, Jazan, Saudi Arabia.
Ahmad AssiriJazan University, Jazan, Saudi Arabia.
Saeed AlshahraniJazan University, Jazan, Saudi Arabia.
Khaled A SahliMinistry of Interior, Riyadh, Saudi Arabia.
Marwa QadriJazan University, Jazan, Saudi Arabia.
Waseem HassanUniversity of Peshawar, Peshawar, Pakistan. waseem_anw@yahoo.com.

Funding

Jazan University,Saudi Arabia JU- 20250296 -DGSSR- RP -2025
6 · The paper itself

Abstract

backgroundLaser therapy is a key acne treatment, yet no bibliometric study has integrated advanced metrics, co-word dynamics, keyword clustering, and citation analysis of the top 100 papers. Three Scopus search strategies were used, and the top 100 most cited papers were analyzed for descriptive statistics and citation impact. The Title-Abstract-Keyword (TAK) search identified 2,352 papers, with output increasing steadily from 2004 and reaching a peak in 2024 (187 papers). The Abstract-only search retrieved 1,209 papers, also peaking in 2024 (98 papers), while the Title-only search yielded 468 papers, with the highest output in 2021 (39 papers). The 100 most cited papers, published between 1986 and 2021, were drawn from 35 sources and comprised 86 original articles and 14 reviews. These papers exhibited no annual growth, had an average age of 16 years, and received an average of 71.54 citations each. From this title-based analysis, several clear research foci emerged: (1) laser resurfacing and fractional CO₂ laser therapy for atrophic acne scars, including comparative trials with Er: YAG and Nd: YAG lasers; (2) pulsed dye lasers and photodynamic therapy for inflammatory acne; (3) diode and nonablative fractional lasers for reducing sebum production and treating scars in diverse skin types; (4) platelet-rich plasma and radiofrequency microneedling as adjuncts to laser therapy to enhance collagen remodeling; and (5) emerging modalities such as picosecond, indocyanine-green, and 675-nm lasers for targeted acne management. These focal areas represent the primary thematic directions of the most influential studies in the field. This first comprehensive bibliometric analysis of laser therapy for acne identifies fractional CO₂ lasers, nonablative fractional lasers, and combination therapies as dominant research themes, while highlighting emerging modalities such as picosecond and 675-nm lasers. These findings align with current clinical priorities and provide a data-driven roadmap for future therapeutic innovation.

Indexed as

Acne VulgarisBibliometricsCicatrixLaser TherapyHumansLasers, GasLow-Level Light TherapyAcne treatmentBibliometric analysisCitation impactCo-word analysisLaser therapyResearch trends

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.