Evidence map›Paper›PMID 40973894›Full record

SynthesisPhysiotherapy research international : the journal for researchers and clinicians in physical therapy2025

Mapping Comorbidities in Patients With Low Back Pain-A Systematic Review.

Jacob S Gandløse, Caroline W M Sørensen, Cecilie T Hemmingsen, Kasper W Larsen, Thorvaldur S Palsson

Abstract readSystematic Review
In one paragraph

Synthesis in Physiotherapy research international : the journal for researchers and clinicians in physical therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Mapping Comorbidities in Patients With Low Back Pain-A Systematic Review.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2025
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jacob S GandløseDepartment of Physiotherapy and Occupational Therapy, Aalborg University Hospital, Aalborg, Denmark.ORCID https://orcid.org/0009-0008-8700-6566
Caroline W M SørensenDepartment of Rehabilitation and Health Promotion Research, Faculty of Health Science, VIA University College, Aarhus, Denmark.
Cecilie T HemmingsenDepartment of Rehabilitation and Health Promotion Research, Faculty of Health Science, VIA University College, Aarhus, Denmark.
Kasper W LarsenDepartment of Rehabilitation and Health Promotion Research, Faculty of Health Science, VIA University College, Aarhus, Denmark.
Thorvaldur S PalssonDepartment of Physiotherapy and Occupational Therapy, Aalborg University Hospital, Aalborg, Denmark.ORCID https://orcid.org/0000-0002-4418-0133

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeLow back pain (LBP) frequently co-occurs with other health conditions, but there is no clear consensus on which comorbidities are most prevalent. This limits understanding of the broader burden and challenges clinical practice.

methodsSystematic searches were conducted in seven databases, including PubMed, Embase, CINAHL, PsycINFO, PEDro, Rehabilitation and Sports Medicine Source, and Cochrane Library. Observational studies on adults (≥ 16 years) with nonspecific LBP and at least three comorbidities were included. Data were extracted, tabulated, and quality assessed using CASP checklists and GRADE classifications.

resultsNine peer-reviewed studies were included. The prevalence of at least one comorbidity ranged from 49% to 92%, with hypertension, osteoarthritis, and chronic pain elsewhere in the body being the most proportionally prevalent comorbidities in individual study populations. Across all studies, hypertension, diabetes, osteoarthritis, asthma, and depression were the most frequently reported comorbidities. Comorbidity assessment, population characteristics, and prevalence varied significantly. Certainty in the prevalence of comorbidities varied from "very low" to "moderate." DISCUSSION: Comorbidities are highly prevalent in adults with LBP. The included studies varied considerably in comorbidity assessment, reporting, and study populations, where sociodemographic factors like sex, age, marital status, education, and employment likely influenced comorbidity prevalence and types. Findings emphasize the need for standardized assessment methods and tailored physiotherapy approaches to address the diverse needs of this population.

Indexed as

Low Back PainAdultComorbidityHumansOsteoarthritisPrevalencecomorbiditieslow back painobservational studiesprevalencesystematic review

Identifiers

PMID40973894
PMCPMC12449286

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.