ArticleJournal of general internal medicine2025
Assessing Anorectal Sexual Function: Validity and Clinical Utility of a New Measure.
Article in Journal of general internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Sexual Toxicity After Chemoradiation for Anal Cancer Among Men Who Have Sex With Men: A Mixed-Methods Analysis.Advances in radiation oncology · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundVarious conditions can disrupt anorectal sexual function, potentially reducing pleasure or increasing pain. There is currently no standard diagnostic criteria for anorectal sexual dysfunction, including anhedonia and anodyspareunia, despite a described need for better measurement tools.
objectiveTo evaluate the Anorectal Sexual Function Index (ASFI) in a clinical sample of people with and without problematic receptive anal intercourse (RAI) and to develop diagnostic cut-off scores for potential classification of sexual dysfunction.
designBetween July 2024 and January 2025, we conducted a mixed-method, cross-sectional study of a population with mixed sexual function/dysfunction among individuals assigned male at birth.
participantsWe recruited individuals with concerns during RAI, including pain or lack of pleasure in addition to people with known pelvic pathology. MAIN MEASURES: All participants completed a clinical interview and a questionnaire, including the ASFI and other health-related quality-of-life measures. KEY
resultsAmong the 122 participants, the mean age was 42 years, the majority (97%) were cis-gender men, and 85% of whom identified as gay. Participants reporting reduced pleasure in the interview scored lower on the pleasure domain (11 vs 17, p < 0.01), while those reporting pain in the interview had higher pain scores (23 vs 13, p < 0.01). Participants with active fissures, IBS, IBD, anal cancer, and chronic prostatitis/pelvic pain syndrome consistently reported higher pain scores and lower pleasure scores. Participants classified with anodyspareunia reported lower sexual satisfaction, reduced erectile frequency during RAI, fewer orgasms during RAI, and higher levels of internalized homophobia. Participants classified with anhedonia reported lower sexual satisfaction, reduced erectile frequency during RAI, fewer orgasms during RAI, and higher prevalence of HIV.
conclusionsWe standardized the diagnosis for anodyspareunia and RAI anhedonia using the ASFI. Respondents with anodyspareunia and RAI anhedonia reported worse patient-reported outcomes than those who did not meet criteria.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.