ArticlePediatric research2026
Histologic chorioamnionitis and fat mass accretion in infants born preterm.
Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Sex-specific outcomes following chorioamnionitis.Pediatric research · 2026Review
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5 authors.
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Abstract
backgroundIn utero insults such as chorioamnionitis are associated with adverse outcomes. This study aims to examine the association between chorioamnionitis and fat mass (FM) in very preterm infants.
methodsWe conducted a retrospective cohort study of mother-infant dyads born <32
resultsAmong 375 mother-infant dyads analyzed, 104 (28%) dyads had MIR. FIR was found in 85 dyads with MIR (82%). Infants without MIR had lower FM in Kg and lower FM z scores than those with MIR (p = 0.0001). Infants with severe MIR had higher body fat percentages (Stage 3: 18% vs Stage 1: 14%, p < 0.0001). There were no significant differences in other anthropometric growth rates. Gestational age partially mediated this association (49%).
conclusionSevere histological chorioamnionitis is associated with greater FM accretion at term-equivalent age, independent of gestational age. Without long-term data, it remains unclear whether this early-onset effect is transient or persists into later childhood. IMPACT STATEMENT: Chorioamnionitis is common in infants born preterm and is strongly associated with preterm birth. Infants born preterm exposed to chorioamnionitis have an increased risk of abnormal fat mass accretion at term equivalent age. Accounting for the severity of chorioamnionitis could improve the interpretation of body fat accretion in infants born preterm.
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