Evidence map›Paper›PMID 40973685›Full record

ArticleBioinformatics (Oxford, England)2025

AXZ viewer: a web application to visualize unprocessed AFM-IR data.

Wouter Duverger, Georg Ramer, Nikolaos Louros, Joost Schymkowitz, Frederic Rousseau

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wouter DuvergerSwitch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, Leuven 3000, Belgium.ORCID 0000-0002-6851-7247
Georg RamerInstitute of Chemical Technologies and Analytics, TU Wien, Vienna 1060, Austria.ORCID 0000-0001-8307-5435
Nikolaos LourosCenter for Alzheimer's and Neurodegenerative Diseases, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, United States.ORCID 0000-0002-4030-1022
Joost SchymkowitzSwitch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, Leuven 3000, Belgium.ORCID 0000-0003-2020-0168
Frederic RousseauSwitch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, Leuven 3000, Belgium.ORCID 0000-0002-9189-7399

Funding

Flanders Institute for BiotechnologyUniversity of Leuven 1128822NUniversity of Leuven I011220N
6 · The paper itself

Abstract

motivationAtomic Force Microscopy-based Infrared spectroscopy (AFM-IR) is a novel and innovative method for label-free high-resolution structural biology. However, the nature of the data files generated by AFM-IR instruments precludes investigation by conventional open-source scientific image analysis software suites. As a result, reporting of AFM-IR datasets is not standardized and the data itself is difficult to audit.

resultsWe have developed a web application that allows anyone to open, review, and audit raw AFM-IR data files easily and without deep knowledge of the method. It also exposes all metadata recorded by the microscope at the time of measurement. The web application is based on a Python package that supports custom data analyses within the scientific Python ecosystem. This tool provides an accessible, transparent solution for AFM-IR data review, with the potential to support reproducibility and standardization in AFM-IR research and encourage wider adoption of this innovative spectroscopy method. AVAILABILITY AND IMPLEMENTATION: The web app is hosted at https://anasys-python-tools-gui.streamlit.app. Its source code is listed at https://github.com/wduverger/anasys-python-tools-gui. The underlying Python package is available at https://github.com/GeorgRamer/anasys-python-tools and can be installed using pip.

Indexed as

Image Processing, Computer-AssistedMicroscopy, Atomic ForceSoftwareInternetSpectrophotometry, Infrared

Identifiers

PMID40973685
PMCPMC12490829

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.