ArticleAJNR. American journal of neuroradiology2026
Photon-Counting CT for Evaluation of Coiled Intracranial Aneurysms.
Article in AJNR. American journal of neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
background and purposeIntracranial aneurysms treated with endovascular embolization often require surveillance imaging using DSA, an invasive, risky, and expensive procedure. Existing noninvasive imaging modalities (standard or MRA) are often unsatisfactory for evaluating treated aneurysms due to artifacts from embolization devices. The objective of the present study was to determine whether photon-counting CT (PCCT) imaging parameters could be optimized to confer satisfactory imaging resolution in an anthropomorphic phantom of treated intracranial aneurysms. MATERIALS AND
methodsPhantom studies were performed using a model of the major intracranial arteries with appropriately sized, endovascularly-treated MCA (coil embolization) and basilar artery (Woven EndoBridge embolization) aneurysms. A series of imaging acquisition procedures was performed using a conventional energy-integrating CT scanner and a PCCT scanner. Key imaging acquisition and reconstruction parameters were varied to identify the optimum protocol for treated aneurysm characterization. Artifact reduction was performed on all images using the iterative metal artifact reduction (iMAR) algorithm (Siemens). Contrast-to-noise ratio (CNR) and metal artifact magnitude were quantitatively analyzed and displayed in tabular form to provide objective criteria for determination of optimal processing parameters for treated aneurysm visualization.
resultsImaging was successfully obtained in phantom studies across a range of imaging parameters. Quantitative metal artifact magnitude was greater for 100 keV virtual monoenergetic images (VMIs) and lowest for 55 keV VMIs without iMAR, but this trend was reversed with iMAR applied. The 55 keV VMI was chosen as the optimal reconstruction parameter for visualization of treated intracranial aneurysms because it demonstrated a low magnitude of metal artifacts and the highest CNR in adjacent vasculature. Similarly, the CNR of the largest vessel adjacent to the coil mass was increased for all images after iMAR was applied. CNR was highest in the 55- keV VMR images both before (3.61 [SD, 0.14]) and after (6.82 [SD, 0.34]) application of iMAR.
conclusionsVirtual monoenergetic images combined with metal artifact reduction algorithms created from PCCT scans conferred excellent visualization of previously-treated intracranial aneurysms and adjacent vasculature. It was feasible to extend these results to preliminary clinical applications in human patients.
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