Evidence map›Paper›PMID 40973349›Full record

ArticleJACC. Case reports2025

Managing Severe Bicuspid Aortic Stenosis, Aortic Coarctation, and Impaired Left Ventricular Function.

Oscar A Perez Orpinel, Félix Damas de Los Santos, Jessy Steve Masso-Bueso, Oscar A Lozano-Cruz, Hugo Rodríguez-Zanella, Javier Molina-Méndez, Alejandro Villalobos, Eduardo A Arias

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Oscar A Perez OrpinelInterventional Cardiology Department, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico.
Félix Damas de Los SantosInterventional Cardiology Department, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico; American British Cowdray Medical Center, Mexico City, Mexico.
Jessy Steve Masso-BuesoInterventional Cardiology Department, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico.
Oscar A Lozano-CruzInterventional Cardiology Department, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico.
Hugo Rodríguez-ZanellaAmerican British Cowdray Medical Center, Mexico City, Mexico; Echocardiography Department, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico.
Javier Molina-MéndezAmerican British Cowdray Medical Center, Mexico City, Mexico; Anesthesiology Department, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico.
Alejandro VillalobosInterventional Cardiology Department, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico.
Eduardo A AriasInterventional Cardiology Department, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico; American British Cowdray Medical Center, Mexico City, Mexico. Electronic address: eduardo.arias@cardiologia.org.mx.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile bicuspid aortic valve and coarctation commonly coexist, diagnosis in the eighth decade of life is exceptionally rare. CASE SUMMARY: A 78-year-old male patient with a history of hypertension was admitted with a 2-year history of progressive dyspnea on minimal exertion. After diagnostic workup, he was diagnosed with severe bicuspid aortic stenosis, aortic coarctation, and severely impaired left ventricle systolic function (left ventricle ejection fraction 12%). Due to high surgical risk, a stepwise percutaneous strategy was adopted, starting with coarctation stenting which improved the left ventricle ejection fraction to 32%, allowing for successful transcatheter aortic valve replacement using a snare-assisted technique. DISCUSSION: Treating the coarctation first facilitated valve delivery and reduced afterload, improving systolic function, and ultimately reducing the need for ventricular support during transcatheter aortic valve replacement. TAKE-HOME MESSAGE: A stepwise approach is crucial in managing high-risk patients with complex structural heart disease, demonstrating the importance of meticulous preprocedural planning.

Indexed as

aortic coarctationbicuspid aortic valvereduced ejection fractionvalve replacement

Identifiers

PMID40973349
PMCPMC12478485

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.