ArticleJACC. Case reports2025
Extensive Right Ventricular Involvement With Thrombus and Myocarditis: An Unanticipated Discovery in Advanced Hepatocellular Carcinoma.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiac involvement in malignancies is rare, with right ventricular tumoral thrombus in hepatocellular carcinoma (HCC) without right atrial extension being exceptionally uncommon. CASE SUMMARY: A 54-year-old man with stage IV HCC experienced recurrent chest discomfort. Stress echocardiography detected an ill-defined inhomogeneous mass, and cardiac magnetic resonance identified right ventricular outflow tract obstruction, left ventricular septal infiltration, and acute-to-subacute myocarditis. Abdominal imaging showed tumor recurrence along with a large thrombus in the retrohepatic inferior vena cava. After multidisciplinary discussions, the patient opted for palliative comfort care. DISCUSSION: Systemic therapy for HCC such as atezolizumab-bevacizumab and lenvatinib may contribute to thrombosis, cardiac dysfunction, and myocarditis. Currently, there are no established guidelines for managing right ventricular tumoral thrombus with outflow tract obstruction complicated by myocarditis, which if untreated could lead to irreversible ventricular dysfunction.
conclusionsThis case highlights the significance of shared decision-making and a multidisciplinary patient-centered approach in optimizing treatment outcomes in complex cardio-oncology care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.