Evidence map›Paper›PMID 40973169›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2025

Improving postoperative length of stay forecasting with retrieval-augmented prediction.

Brian H Park, Chun-Nan Hsu, Austin Nguyen, Ying Q Zhou, Rodney A Gabriel

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brian H ParkDivision of Perioperative Informatics, Department of Anesthesiology, University of California San Diego, La Jolla, CA 92037, United States.
Chun-Nan HsuDivision of Perioperative Informatics, Department of Anesthesiology, University of California San Diego, La Jolla, CA 92037, United States.
Austin NguyenSchool of Medicine, University of California San Diego, La Jolla, CA 92037, United States.
Ying Q ZhouDivision of Perioperative Informatics, Department of Anesthesiology, University of California San Diego, La Jolla, CA 92037, United States.ORCID 0000-0003-3667-1183
Rodney A GabrielDivision of Perioperative Informatics, Department of Anesthesiology, University of California San Diego, La Jolla, CA 92037, United States.

Funding

San Diego Biomedical Informatics Education & Research (SABER)T15LM011271 · NLM · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHAMIM NEMATI · 2012 to 2026
$9.7M
Co-Design and Collaborative Development of an Imaging-Text-EHR Multimodal Foundation Model for Outcome Prediction of Critically Ill PatientsOT2OD037995 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Rodney Allanigue Gabriel, Chunnan Hsu · 2025 to 2026
$1.7M
Interdisciplinary Anesthesiology Research Training ProgramT32GM121318 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Hemal H Patel, DAVID M ROTH · 2017 to 2026
$1.5M
NIGMS NIH HHS T32 GM121318NIGMS NIH HHS T32GM121318NIH HHS OT2 OD037995NLM NIH HHS T15 LM011271
6 · The paper itself

Abstract

objectiveThe objective of this study is to evaluate retrieval-augmented prediction for forecasting hospital length of stay (LOS) following surgery compared to traditional machine learning (ML), standalone large language models (LLMs), and retrieval-augmented generation (RAG) approaches. MATERIALS AND

methodsSpine surgery cases were extracted from electronic health records. Structured features and operative notes were concatenated into natural language patient representations, embedded using Sentence-Bidirectional Encoder Representations from Transformer, and stored in a vector database. Eight predictive models were implemented, including a baseline model, standalone ML with embeddings, standalone LLM (Gemma 3:27B), and combinations of these with retrieval-augmented prediction or generation. The retrieval-augmented prediction model computed a similarity-weighted average LOS from nearest neighbors. Performance was assessed using R2, mean absolute value (MAE), and root mean square error (RMSE).

resultsRetrieval-augmented prediction alone outperformed standalone ML and LLM models (R2 = 0.39, MAE = 4.47). Combining ML or LLM outputs with retrieval-augmented prediction further improved performance. The best performing model was a neural network blended with retrieval-augmented prediction (R2 = 0.52, MAE = 4.16). LLM-RAG alone reached R2 = 0.19, which improved to 0.47 when combined with retrieval-augmented predictions. Retrieval-augmented prediction consistently reduced MAE and RMSE by up to 32% and 38%, respectively. DISCUSSION: Retrieval-augmented prediction offers interpretable and resource-efficient forecasting by semantically leveraging prior patient cases without generative modeling. It consistently outperformed RAG and ML across metrics, approximating clinical reasoning via similarity-based inference.

conclusionRetrieval-augmented prediction significantly enhances LOS prediction accuracy over standard ML and LLM models. Its interpretability and scalability make it a promising solution for integrating predictive analytics into clinical workflows.

Indexed as

Electronic Health RecordsLength of StayMachine LearningNatural Language ProcessingSpineForecastingHumanslarge language modellength of staymachine learningnatural language processingspine/surgery

Identifiers

PMID40973169
PMCPMC12836098

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.