Evidence map›Paper›PMID 40973061›Full record

GuidelineNeuro-oncology2026

EANS-EANO guidelines on the extent of resection in gliomas.

Roland Goldbrunner, Nicolas Foroglou, Francesco Signorelli, Philippe Schucht, Asgeir S Jakola, Giuseppe Minniti, Radoslaw Rola, Mirjam Renovanz, Matthias Preusser, Julia Furtner and 5 more

Abstract readPractice Guideline
In one paragraph

Guideline in Neuro-oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  16. Hemizygous deletion ofNeuro-oncology advances
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Roland GoldbrunnerDepartment of General Neurosurgery, Center for Neurosurgery, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.ORCID 0000-0002-1927-0022
Nicolas ForoglouDepartment of Neurosurgery, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Francesco SignorelliDivision of Neurosurgery, Department of Translational Biomedicine and Neurosciences, University "Aldo Moro" of Bari, Bari, Italy.
Philippe SchuchtDepartment of Neurosurgery, Bern University Hospital, Bern, Switzerland.
Asgeir S JakolaSection of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Gothenburg, Sweden.
Giuseppe MinnitiDepartment of Radiological Sciences, Oncology, and Anatomical Pathology, Sapienza University of Rome, Rome, Italy.
Radoslaw RolaDepartment of Neurosurgery and Pediatric Neurosurgery, Medical University of Lublin, Lublin, Poland.
Mirjam RenovanzDepartment of Neurology and Interdisciplinary Neuro-Oncology, University Hospital Tübingen, Hertie Institute for Clinical Brain Research, Eberhard Karls University, Tübingen, Germany.
Matthias PreusserDivision of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
Julia FurtnerResearch Center MIAAI (Medical Image Analysis and Artificial Intelligence), Danube Private University, Krems-Stein, Austria.
Rachel GrossmanBrain Tumor Center, Department of Neurosurgery, Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Christian MawrinDepartment of Neuropathology, Otto-Von-Guericke University, Magdeburg, Germany.
Andreas DemetriadesDepartment of Neurosurgery, Royal Infirmary, Edinburgh, UK.ORCID 0000-0002-2004-9448
Michael WellerDepartment of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.ORCID 0000-0002-1748-174X
Matthias SimonDepartment of Neurosurgery, Bethel Clinic, University of Bielefeld, Medical Center Ostwestfalen-Lippe, Bielefeld, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intense efforts are employed to optimize neurosurgical resection of gliomas in different clinical scenarios. However, the level of evidence employed toward personalized treatment decisions is still moderate. Therefore, a joint task force was created by the European Association for Neurosurgical Societies (EANS) and the European Association of Neuro-Oncology (EANO) in order to provide interdisciplinary guidance on the extent of resection (EOR) in glioma surgery. This task force assessed the data on the EOR in gliomas, evaluated the level of evidence, and composed recommendations. The EOR is determined routinely by postoperative magnetic resonance imaging. Since EOR may be associated with survival and may have an impact on epilepsy, neurocognition, quality of life, neurological status, and also on planning of radiation and pharmacotherapy (evidence classes I-IV), recommendations of different levels can be made for the resection of newly diagnosed glioblastomas (level A), recurrent glioblastomas (level C), newly diagnosed (level B) and recurrent (good practice point) IDH mutant gliomas, ependymomas in children (level B) and adults (good practice point) as well as World Health Organization CNS grade 1 tumors (good practice point). We hereby report the outcome of this collaborative effort by the joint task force between EANS and EANO.

Indexed as

Brain NeoplasmsGliomaNeurosurgical ProceduresPractice Guidelines as TopicHumansSocieties, Medicalglioblastomagliomaprognosisresectionsurgerysurvival

Identifiers

PMID40973061
PMCPMC12962633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.