Evidence map›Paper›PMID 40972239›Full record

ReviewCurrent opinion in plant biology2025

DNA methylation dynamics: patterns, regulation, and function.

Jia Gwee, Wenwen Tian, Shuiming Qian, Xuehua Zhong

Abstract readReview
In one paragraph

Review in Current opinion in plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jia GweeDepartment of Biology, Washington University in St Louis, St Louis, MO 63130, USA.
Wenwen TianDepartment of Biology, Washington University in St Louis, St Louis, MO 63130, USA.
Shuiming QianDepartment of Biology, Washington University in St Louis, St Louis, MO 63130, USA.
Xuehua ZhongDepartment of Biology, Washington University in St Louis, St Louis, MO 63130, USA. Electronic address: xuehuazhong@wustl.edu.

Funding

Uncovering the epigenetic codes for genome integrity, developmental and environmental interaction.R35GM124806 · NIGMS · WASHINGTON UNIVERSITY · PI XUEHUA ZHONG · 2017 to 2026
$4.2M
NIGMS NIH HHS R35 GM124806
6 · The paper itself

Abstract

As the crucial interface between the genome and the environment, the epigenome plays a key role in plant survival and thriving. Despite the identical DNA sequence in each nucleus of an individual, its interpretation by the cell is governed by both spatial and environmental contexts. The field of plant epigenetics is advancing rapidly with groundbreaking discoveries that are transforming our knowledge of how plants regulate gene expression, adapt to environmental changes, and uphold genomic stability. Recent technological advancements have also dramatically enhanced our ability to study the epigenome with precision, offering insights into its role at an unprecedented scale. Here, we highlight the latest findings focusing on the intricate balance of DNA methylation, the dynamic and multi-layered regulatory mechanisms, and the role and evolutionary significance of DNA methylation variations across diverse plant species. Understanding these variations in DNA methylation offers crucial insights into how plant epigenetic mechanisms regulate gene expression, genome organization, development, and responses to environmental changes.

Indexed as

DNA MethylationEpigenesis, GeneticGene Expression Regulation, PlantPlantsGenome, Plant

Identifiers

PMID40972239
PMCPMC13054798

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.