Evidence map›Paper›PMID 40971919›Full record

ArticleSchizophrenia bulletin2026

Clinical Significance of Psychotic Experiences in Preadolescent Children with Non-Psychotic Mental Disorders-The Danish High Risk and Resilience Study, VIA 11.

Maja Gregersen, Sinnika Birkehøj Rohd, Anne Søndergaard, Julie Marie Brandt, Jens Richardt Møllegaard Jepsen, Lotte Veddum, Christina Bruun Knudsen, Anna Krogh Andreassen, Carsten Hjorthøj, Mette Falkenberg Krantz and 5 more

Abstract read
In one paragraph

Article in Schizophrenia bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Maja GregersenChild and Adolescent Mental Health Center, Mental Health Services in the Capital Region of Denmark, Hellerup, Denmark.ORCID 0000-0002-6510-1449
Sinnika Birkehøj RohdCORE-Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Mental Health Services in the Capital Region of Denmark, Copenhagen, Denmark.
Anne SøndergaardCORE-Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Mental Health Services in the Capital Region of Denmark, Copenhagen, Denmark.
Julie Marie BrandtCORE-Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Mental Health Services in the Capital Region of Denmark, Copenhagen, Denmark.
Jens Richardt Møllegaard JepsenChild and Adolescent Mental Health Center, Mental Health Services in the Capital Region of Denmark, Hellerup, Denmark.
Lotte VeddumThe Lundbeck Foundation Initiative for Integrative Psychiatric Research-iPSYCH, Aarhus, Denmark.
Christina Bruun KnudsenThe Lundbeck Foundation Initiative for Integrative Psychiatric Research-iPSYCH, Aarhus, Denmark.
Anna Krogh AndreassenThe Lundbeck Foundation Initiative for Integrative Psychiatric Research-iPSYCH, Aarhus, Denmark.
Carsten HjorthøjCORE-Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Mental Health Services in the Capital Region of Denmark, Copenhagen, Denmark.ORCID 0000-0002-6943-4785
Mette Falkenberg KrantzChild and Adolescent Mental Health Center, Mental Health Services in the Capital Region of Denmark, Hellerup, Denmark.
Aja Neergaard GreveThe Lundbeck Foundation Initiative for Integrative Psychiatric Research-iPSYCH, Aarhus, Denmark.ORCID 0000-0002-1369-6639
Ole MorsThe Lundbeck Foundation Initiative for Integrative Psychiatric Research-iPSYCH, Aarhus, Denmark.
Merete NordentoftCORE-Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Mental Health Services in the Capital Region of Denmark, Copenhagen, Denmark.
Nicoline HemagerChild and Adolescent Mental Health Center, Mental Health Services in the Capital Region of Denmark, Hellerup, Denmark.ORCID 0000-0003-1339-9981
Anne Amalie Elgaard ThorupChild and Adolescent Mental Health Center, Mental Health Services in the Capital Region of Denmark, Hellerup, Denmark.

Funding

Beatrice Surovell Haskell Fund for Child Mental Health Research of Copenhagen 11531Independent Research Fund Denmark 2096-00065BInnovation Fund 6152-00002BLundbeck Foundation Initiative for Integrative Psychiatric Research-iPSYCH R248-2017-2003
6 · The paper itself

Abstract

background and hypothesisPsychotic experiences (PE) are associated with higher severity of other psychopathology in adults and adolescents with non-psychotic mental disorders. Knowledge on the clinical significance of PE in children with non-psychotic mental disorders, which may help improve early identification of need for treatment, is sparse. STUDY

designIn this cross-sectional study, preadolescent children (n = 157, mean age 12.0, SD 0.2, range 11.1-12.7 years) at familial high-risk of schizophrenia (n = 78) or bipolar disorder (n = 40) and population-based controls (n = 39) with non-psychotic Axis I mental disorders during middle childhood were assessed for PE, dimensional psychopathology, multimorbidity, global functioning, and impact of psychopathology. STUDY

resultsChildren with PE had higher scores on total (Cohen's d 0.40, P = .02) and internalizing dimensional symptoms (Cohen's d 0.42, P = .02) and higher rates of multimorbidity, ie, meeting criteria for more than one mental disorder (OR 2.2, P = .04), than those without PE after accounting for familial risk. Children with PE had higher rates of self-reported impact of psychopathology after accounting for number of concurrent mental disorders and familial risk (OR 2.5, P = .01). The levels of externalizing symptoms and global functioning were not significantly different in those with and without PE.

conclusionsPresence of PE marks increased severity of concurrent non-psychotic psychopathology including more self-perceived impact of psychopathology in preadolescent children with mental disorders. PE could indicate a higher need for treatment and should be routinely assessed in child and adolescent mental health services.

Indexed as

Bipolar DisorderMental DisordersPsychotic DisordersSchizophreniaChildComorbidityCross-Sectional StudiesDenmarkFemaleHumansMaleRiskadolescencechildhoodpsychopathologysubclinical psychosis

Identifiers

PMID40971919
PMCPMC13391611

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.